PubMed Health⌕ Search

Biomedical subjects

Boris Furman

Publications and source records attributed to Boris Furman.

3 recordsLinked to original sources

Invasive genetic diagnosis in multiple pregnancies.

Chromosomal anomalies and mendelian diseases are more frequent in multiple gestations than in singletons. Prenatal diagnosis is recommended in multiple pregnancies whenever indicated. Invasive testing using amniocentesis or chorionic villus sampling can be performed safely. Chorionic villus sampling has a significant advantage over amniocentesis because it offers rapid karyotyping and biochemical and DNA studies at an early stage of pregnancy. Only experienced centers should perform these procedures because of the technical aspects and the expertise needed in handling discordant results.

Abortion, Spontaneous↗

A randomized trial comparing a 30-mL and an 80-mL Foley catheter balloon for preinduction cervical ripening.

OBJECTIVES: The purpose of this study was to compare the efficacy of cervical ripening with 2 Foley catheter balloon volumes. STUDY DESIGN: Pregnant women admitted for induction of labor with a term singleton gestation were randomly assigned for cervical ripening by a balloon inflated with 30 mL or 80 mL of sterile saline. RESULTS: Two hundred and three women were included in the analysis. Ripening of the cervix with the larger balloon volume was associated with a significantly higher rate of post-ripening dilatation of 3 cm or more (76.0% vs 52.4%, P < .001). In primiparous women, the larger balloon volume resulted in a significantly higher rate of deliveries by 24 hours (71.4% vs 49%, P < .05), and a significantly less requirement of augmentation with oxytocin (69.3% vs 90.4%, P < .05). CONCLUSION: Ripening of the unfavorable cervix in primiparous women with a Foley catheter balloon inflated with 80 mL provided effective more dilatation, faster labor, and decreased need for oxytocin than with a balloon inflated with 30 mL of sterile saline.

Adult↗

[Chickenpox during pregnancy].

Chickenpox during pregnancy is very uncommon and is known to cause fatal malformation during the first half of pregnancy. The infection during pregnancy is also associated with maternal morbidity and mortality. Furthermore, there may also be neonatal complications. Thus, any pregnant woman with Varicella infection should be hospitalized and followed-up closely. In this review, we examined the literature on Varicella Zoster during pregnancy with regard to prevalence, prenatal diagnosis, management and prevention.

Chickenpox↗