Biomedical subjects

Branislav Jovanović

Publications and source records attributed to Branislav Jovanović.

5 recordsLinked to original sources

PubMed2004

[Laparoscopic operations in pediatric surgery].

From January 2003 to January 2004, laparoscopy was performed in 100 cases, aged from 10 months to 19 years. Diagnostic laparoscopy was applied in 39 patients, most often in nonpalpable testes (29), ovarian cysts (4), abdominal trauma (1), abdominal cysts (2) and intersex states (3). Ninety patients underwent operative laparoscopy: appendectomy (44), orchiopexy (2), orchiectomy (1), herniorrhaphy (1), varicocelectomy (8), adnexectomy (2), cholecystectomy (8), Fowler-Stephens procedure (1), abdominal cysts (2), ovarian cystectomy (6), subdiaphragmatic abscess (1), adhesiotomy (11), liver cysts (2) and splenectomy (1). Diagnostic laparoscopy has proved to be more reliable and less invasive method in comparison to previously used methods. Our conclusion is that operative laparoscopy has many advantages compared with some of the classical surgical procedures.

Adolescent↗

PubMed2004

[Laparoscopic appendectomy in children--a new fashion or a privilege].

Whether laparoscopic appendectomy is superior to open appendectomy for simple and perforated appendicitis in children is still debatable. To answer this question, surgical experience of three experienced pediatric surgeons in a single institution was studied during one year in all cases of laparoscopic appendectomy. From January 2003 to January 2004, all laparoscopic appendectomies were reviewed for operative technique, advantages, disadvantages, operative time and length of stay. There were 44 laparoscopic appendectomies in children aged 4 to 19 years. Operating time dropped from 52 minutes at the beginning to less than 25 minutes at the end of year. Operating time in perforated appendicitis was slightly longer, from 58-65 minutes. Length of stay was 1-2 days for simple cases, and maximum 5 days for perforated ones. There were no postoperative complications such as abscess, bowel obstruction, bleeding, wound infection or mortality. Laparoscopic appendectomy is at least as safe and effective, if not superior to, as open appendectomy for both, simple and perforated appendicitis. Postoperative pain is less, and recovery is faster. Laparoscopic appendectomy is our procedure of choice in pediatric surgery.

Adolescent↗

PubMed2004

[Surgery for neutropenic enterocolitis, a complication in acute lymphoblastic leukemia].

Neutropenic enterocolitis (NE) is an unusual acute complication of neutropenia, associated with leukemia and lymphoma. It has been observed mainly in the first phase of therapy when drugs are used in maximally tolerated dose. This is a case report of neutropenic enterocolitis in a patient with acute lymphoblast leukemia who received prednisone, vincristine, daunorubicin and L-asparaginase, with perforation of cecal and terminal ileum. Perforation and defect intestine wall was excised and sutured directly in two layers. Protective proximal loop ileostomy was performed at that time.

Adolescent↗

PubMedDate not supplied

[An epidemic of tularemia in the Nish area].

Tularaemia, as a rare disease, surprised medical workers in 1999 and 2000 when it was detected and diagnosed in 31 patients. In 1999 patients were registered in villages of the Sokobanja community, and in 2000 also in other communities in the district of Nish. Patients were peasants, mostly housewives. Glandular form of the disease was dominant. The main clinical symptoms were: tonsillitis, pain in the region of enlarged lymphatic glands and temperature, Biohumoral syndrome presented accelerated sedimentation of erythrocytes and elevated fibrinogen values. Antibody titer of Francisella tularensis was extremely high in the majority of patients. The disease was cured in all patients: in 27 patients after the first therapy, in 4 subjects after recidivation and 5 patients were surgically treated.

Adolescent↗

PubMedDate not supplied

[Histopathologic and immunocytochemical changes in the liver in patients with chronic hepatitis C].

BACKGROUND: The presence of lymphocytes within the liver parenchyma is related to immunologically mediated liver damage in chronic hepatitis C. The aim of the study was to make histological, histochemical, and immunocytochemical assessment of liver biopsy specimens in patients with chronic hepatitis C virus (HCV) infection. METHODS: Biopsy specimens of 20 patients with chronic HCV disease were analyzed, using standard staining procedures to verify histologic liver lesions, as well as immunoenzymatic staining with monoclonal antibodies to detect CD4+ T-lymphocytes, B-lymphocytes, and macrophages. RESULTS: Micromorphologic characteristics of chronic active viral hepatitis C were present in all the patients, differing, however, by the level of their activity. Dominant changes were found within the portal space, consisting of mononuclear lympho-plasmocytic infiltration and macrophages. Immunocytochemical investigation of mononuclear and macrophageal infiltration showed the correlation between micromorphological findings and the degree of the activity. CONCLUSION: The presence of lymphocytic and macrophageal infiltration within the hepatic tissue directly correlated with the intensity of the liver damage. Analysis of the population of cellular infiltrate in the liver together with the monitoring of viremia level and the level of hepatocyte necrosis, could be useful tools for elucidation of the pathogenesis of chronic hepatitis C.

Adult↗