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Biomedical subjects

Brett A Taylor

Publications and source records attributed to Brett A Taylor.

5 recordsLinked to original sources
PubMed2006

Racial variation in treatment preferences and willingness to randomize in the Spine Patient Outcomes Research Trial (SPORT).

STUDY DESIGN: Analysis of baseline data for patients enrolled in Spine Patient Outcomes Research Trial (SPORT), a project conducting three randomized and three observational cohort studies of surgical and nonoperative treatments for intervertebral disc herniation (IDH), spinal stenosis (SpS), and degenerative spondylolisthesis (DS). OBJECTIVE: To explore racial variation in treatment preferences and willingness to be randomized. SUMMARY OF BACKGROUND DATA: Increasing minority participation in research has been a priority at the NIH. Prior studies have documented lower rates of participation in research and preferences for invasive treatment among African-Americans. METHODS: Patients enrolled in SPORT (March 2000 to February 2005) that reported data on their race (n = 2,323) were classified as White (87%), Black (8%), or Other (5%). Treatment preferences (nonoperative, unsure, surgical), and willingness to be randomized were compared among these groups while controlling for baseline differences using multivariate logistic regression. RESULTS.: There were numerous significant differences in baseline characteristics among the racial groups. Following adjustment for these differences, Blacks remained less likely to prefer surgical treatment among both IDH (White, 55%; Black, 37%; Other, 55%, P = 0.023) and SpS/DS (White, 46%; Black, 30%; Other, 43%; P = 0.017) patients. Higher randomization rates among Black IDH patients (46% vs. 30%) were no longer significant following adjustment (odds ratio [OR] = 1.45, P = 0.235). Treatment preference remained a strong independent predictor of randomization in multivariate analyses for both IDH (unsure OR = 3.88, P < 0.001 and surgical OR = 0.23, P < 0.001) and SpS/DS (unsure OR = 6.93, P < 0.001 and surgical OR = 0.45, P < 0.001) patients. CONCLUSIONS: Similar to prior studies, Black participants were less likely than Whites or Others to prefer surgical treatment; however, they were no less likely to agree to be randomized. Treatment preferences were strongly related to both race and willingness to be randomized.

Adult↗
PubMed2005

Increased risk of postoperative neurologic deficit for spinal surgery patients with unobtainable intraoperative evoked potential data.

STUDY DESIGN: This was a retrospective study of 4,310 patients undergoing spinal surgery between 1994 and 2003. OBJECTIVES: To examine the incidence and potential causality of unobtainable somatosensory evoked potential (SSEP) and neurogenic mixed evoked potential (NMEP) data for a population of spinal surgery patients. SUMMARY OF BACKGROUND DATA: Patients with absent or unobtainable evoked potential data may increase the risk of undetected neurologic injury. To date, a comprehensive review of this patient population has not been reported. METHODS: A total of 4,310 consecutive orthopedic spinal surgeries at one institution from January 1994 through December 2003 were reviewed. Cases lacking sufficient monitoring data, despite functional neural integrity (ambulators, intact sensation), were identified. Diagnoses were divided into six general categories. The association between absent evoked potential data and associated neurologic and/or medical pathology was evaluated. RESULTS: A total of 59 of 4,310 cases (1.37%) had absent SSEP and/or NMEP intraoperative data despite functional neural integrity (44 ambulators/15 nonambulators)" 5.08% of study patients awoke with increased neurologic deficit (3 of 59), 2 global deficits, and 1 nerve root deficit. The incidence of postoperative neurologic deficit in the entire surgical population was 0.77% (33 of 4,310), 8 global (0.19%), and 25 nerve root deficits (0.058%). A Fisher's exact test demonstrated a statistically significant difference between the incidence in these two populations (P = 0.0121) and the incidence of global paraplegic deficits (P = 0.0075). CONCLUSION: Patients with unobtainable data pose a much higher risk (P = 0.0121) for postoperative neurologic deficits. Multiple Stagnara wake-up tests are strongly recommended when evoked potential data cannot be obtained.

Adolescent↗
PubMed2005

Differences in the work-up and treatment of conditions associated with low back pain by patient gender and ethnic background.

STUDY DESIGN: Retrospective review comparing physician workup of degenerative lumbosacral pathologies between different genders and ethnic groups. OBJECTIVES: To investigate whether patient ethnicity and gender influence the workup and treatment of degenerative spinal pathologies. SUMMARY OF BACKGROUND DATA: Data from numerous studies suggest that patient gender and ethnicity play a role in medical decision-making, with white males receiving more frequent interventions than women and minorities. METHODS: Patients enrolled for an "initial visit" in the National Spine Network database with lumbosacral level degenerative diagnosis were reviewed. Variables included patient gender, ethnicity, age, duration of symptoms, patient-graded severity of symptoms, radicular symptom pattern, and work status. RESULTS: We identified 5690 patients with degenerative lumbosacral pathologies. Although females were more likely than males to have imaging tests ordered, male (18.5%) patients were significantly more likely to have surgery recommended than female (16.3%) patients (P < 0.031). Nonwhite females were 52% less likely to have surgery offered at initial visit, as compared to white males (P < 0.005). More imaging tests were ordered or reviewed among whites (76.6%) than among any other ethnic group (P = 0.162). White (18.3%) and Asian (22.5%) patients were significantly more likely to have surgery recommended or prescribed than black (11.1%) and Hispanic (14.5) patients (P < 0.0001). CONCLUSIONS: This study suggests that ethnicity and gender affect the workup and surgical management of degenerative spinal disorders. However, it should be noted that there are a number of confounding factors not identified in the database, including managed care and insurance status and cultural differences, which may affect both test ordering and treatment recommendations. Further study of bias in clinical decision-making is indicated to assure equal delivery of quality care.

Black or African American↗
PubMed2004

Percutaneous reduction of incipient malunion of phalangeal neck fractures in children.

PURPOSE: In this article we describe our treatment of partially healed malaligned fractures of the phalangeal neck in children. METHODS: This was a retrospective study of 8 pediatric patients with phalangeal neck fractures who presented late for care to Children's Hospital in Boston. All patients were diagnosed clinically and radiographically with advanced partial healing of their fracture in a malunited position of extension. The 8 patients were followed up until fracture healing and restoration of normal motion and function were achieved. RESULTS: A K-wire was inserted into the fracture site through the dorsal callus and used to mobilize the fracture fragment by breaking down the fracture callus and partially healed bone. The wire then was used as a lever arm for fracture reduction. A separate wire was used to pin the fracture percutaneously. CONCLUSIONS: This treatment corrects the loss of flexion that occurs with a malunion in the phalangeal subcondylar fossa. It is a minimally invasive procedure that avoids the soft-tissue dissection of an open procedure.

Adolescent↗