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Biomedical subjects

Brian Berman

Publications and source records attributed to Brian Berman.

64 records · Page 4Linked to original sources
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Cutaneous signs and syndromes associated with internal malignancies.

Cutaneous changes may indicate the presence of or herald the incipient development of internal malignancies. The authors review 24 cutaneous signs, symptoms, diseases, and syndromes associated with internal malignancies. Early recognition of these cutaneous changes may allow for vigilance for, and prompt detection and management of, the underlying neoplasm.

Humans↗
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Skin disease in a primary care practice.

OBJECTIVE: Family medicine physicians treat a large amount of skin disease. Yet, information is lacking regarding which dermatologic disorders are more likely to present to a family medicine physician. Therefore, we performed a chart review at a family medicine private practice in Islamorada, FL, to determine the percentage of patients presenting with dermatologic disease and to identify the most common diseases encountered. DISCUSSION: On 12 office days in May 2004 to June 2004, 21% of patients seen by a family medicine physician had at least one skin problem, which was the chief complaint 72.2% of the time. CONCLUSIONS: Infectious etiology and inflammatory conditions accounted for the majority of skin disease diagnosed by the physician. Geography and demographics are of great importance when considering which dermatologic diseases are most likely to present to a given physician.

Demography↗
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The variability of TCM pattern diagnosis and herbal prescription on rheumatoid arthritis patients.

CONTEXT: The consistency of diagnosis made among Traditional Chinese Medicine (TCM) practitioners and the relationship between TCM diagnosis and Chinese herbal prescription have not been adequately examined. OBJECTIVE: To investigate the degree of consistency with which TCM diagnoses and herbal prescriptions can be made by practitioners examining rheumatoid arthritis (RA) patients. To survey TCM diagnostic patterns and to examine the correlation between herbal prescriptions and these diagnoses for a sample of RA patients. DESIGN: A prospective survey. SETTING: General Clinical Research Center, University of Maryland Hospital System, Baltimore, MD. PATIENTS: Rheumatoid arthritis patients. PRACTITIONERS: Licensed acupuncturists with a minimum of 5 years licensure and education in Chinese herbs. METHODS: Three TCM practitioners examined the same 39 RA patients separately, following the traditional "Four Diagnostic Methods." Patients filled out a questionnaire to serve as the data for the "Inquiry" component. They then underwent a physical examination, including the tongue and pulse, conducted by each of the practitioners. Based upon the examination results, each practitioner provided both a TCM diagnosis and a herbal prescription. These diagnoses/prescriptions were then examined with respect to the rate of agreement among the 3 practitioners. RESULTS: The average agreement with respect to the TCM diagnoses among the 3 pairs of TCM practitioners was 28.2% (25.6 to 33.3% with kappas ranging from 0.23 to 0.30). The degree to which the herbal prescriptions agreed with textbook recommended practice of each TCM diagnosis was 93.2% (range = 87.2 to 100%). CONCLUSION: The total agreement on TCM diagnosis on RA patients among 3 TCM practitioners was low. When less stringent, but theoretically justifiable, criteria were employed, greater consensus was obtained among the 3 practitioners. The correspondence between the TCM diagnosis and the herbal formula prescribed for that diagnosis was high, although there was little agreement among the 3 practitioners with respect to the herbal formulas prescribed for individual patients.

Adult↗
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Immunomodulators for skin cancer.

Therapeutic interventions to augment tumor antigenicity or increase the host's immune response against cancer cells include recombinant cytokines, immune modulators, vaccination with tumor antigens, T cell-based immunotherapy, and gene therapy. We describe the current role of the immunomodulators (up-regulators of the immune response) in the therapy of skin cancer (non melanoma skin cancer, melanoma, lymphoma, Kaposi sarcoma, and extramammary Paget's disease).

Aminoquinolines↗