Biomedical subjects

Bruno M Carvalho

Publications and source records attributed to Bruno M Carvalho.

2 recordsLinked to original sources

PubMed2005

MamMiBase: a mitochondrial genome database for mammalian phylogenetic studies.

UNLABELLED: MamMiBase, the mammalian mitochondrial genome database, is a relational database of complete mitochondrial genome sequences of mammalian species. The database is useful for phylogenetic analysis, since it allows a ready retrieval of nucleotide and aminoacid individual alignments, in three different formats (NEXUS for PAUP program, for MEGA program and for PHYLIP program) of the 13 protein coding mitochondrial genes. The user may download the sequences that are useful for him/her based on their parameters values, such as sequence length, p-distances, base content, transition transversion ratio, gamma, which are also given by MamMiBase. A simple phylogenetic tree (neighbor-joining tree with Jukes Cantor distance) is also available for download, useful for parameter calculations and other simple tasks. AVAILABILITY: MamMiBase is available at http://www.mammibase.lncc.br

Chromosome Mapping↗

PubMed2005

Visualization of treatment evolution using hardware-accelerated morphs.

The observation of the evolution of a course of treatment can provide a powerful tool in understanding its efficacy. To visualize this, we produce animations allowing the visualization, as a function of time, of lesions in an organ. Such animations can be used in teaching or for patient education, influencing a patient's decision of following a course of treatment. The animation produced is a metamorphosis, or morph, describing how a source shape (pre-treatment) gradually deforms into a target shape (post-treatment). We implemented our method using the programming capabilities of current graphics cards (also known as graphics processing units or GPUs), so both visualization of the volumes and morph generation are performed in real-time. We demonstrate our method on data from a patient's liver with lymphoma that was treated with chemotherapy and is currently on remission.

Computer Graphics↗