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Biomedical subjects

C A Calvert

Publications and source records attributed to C A Calvert.

At least 37 records · Page 2Linked to original sources
PubMed1986

Use of M-mode echocardiography in the diagnosis of congestive cardiomyopathy in Doberman pinschers.

M-mode echocardiography performed on 3 groups of Doberman Pinschers--healthy, early cardiomyopathy, and advanced cardiomyopathy (pulmonary edema present). Echocardiographic measurements in those dogs with advanced cardiomyopathy were typical of the disease in human beings and other breeds of dogs. Significant differences were detected between dogs with early cardiomyopathy and those with advanced disease. The E-point septal separation was determined to be the most sensitive and specific criterion for the recognition of early cardiomyopathy.

Age Factors↗
PubMed1985

Cardiovascular infections in dogs: epizootiology, clinical manifestations, and prognosis.

Bacteremia in dogs was found to be more prevalent than suspected and Staphylococcus aureus, Escherichia coli, and beta-hemolytic streptococci were the most commonly isolated microbes. Administration of glucocorticoids was the most common predisposing cause of infections. Subacute and chronic bacteremia often followed integumentary infections such as abscesses, cellulitis, and infected wounds and was usually the result of gram-positive microbes. Peracute and acute bacteremia was associated with internal infections and was usually the result of E coli. Many dogs with bacteremia had unusual or multisystemic signs similar to those observed with immune-mediated diseases. Hypotension, tachycardia, and weakness were features of gram-negative bacteremia, whereas gram-positive bacteremia had more chronic signs and tended to develop into diskospondylitis. The adequacy of treatment, type of bacteremia, source of infection, and delay before treatment influenced the course of illness. Cephalosporins and gentamicin were most effective against all types of bacteremia.

Alkaline Phosphatase↗
PubMed1985

Pneumonitis associated with occult heartworm disease in dogs.

Nine of 69 dogs with occult heartworm disease (13%) had allergic pneumonitis characterized by consistent clinical and radiographic signs. Although the clinical signs were severe, the degree of radiographic pulmonary arterial abnormalities was mild. Corticosteroid therapy resulted in rapid resolution of clinical and radiographic signs; thiacetarsamide therapy was then given without complications. This syndrome may not be recognized as heartworm-associated and may be confused with other disorders, some being associated with a poor prognosis and requiring different therapy.

Animals↗
PubMed1985

Pulmonary manifestations of heartworm disease.

The clinical signs associated with heartworm disease are the result of changes in the pulmonary arterial system. These clinical signs are the result of either pulmonary hypertension or lung parenchymal disease associated with vascular changes. An increase in pulmonary arterial pressure produces an increase in right ventricular afterload, which may lead to exercise intolerance, syncope, and right-sided congestive heart failure. Coughing, dyspnea, and hemoptysis are the results of pulmonary parenchymal disease.

Adrenal Cortex Hormones↗
PubMed1983

Immunosuppressive effects of cyclophosphamide, vincristine, and L-asparaginase in dogs.

The acute effects of cyclophosphamide, vincristine, and L-asparaginase on the humoral and cell-mediated immune responses in dogs were evaluated. Dogs were given a single dose of cyclophosphamide (10 mg/kg of body weight, IV), a single dose of vincristine (0.025 mg/kg, IV), a single dose of L-asparaginase (400 U/kg, IV), or a combination of these drugs at the aforementioned dosages administered simultaneously. The total number of leukocytes decreased significantly (P = less than 0.05) on posttreatment day 3 in the cyclophosphamide-treated dogs. Antibody responses and lymphocyte blastogenesis were not affected. A transient lymphopenia on posttreatment day 1 was the only response seen in the vincristine-treated dogs. Antibody responses to sheep RBC and lymphocyte blastogenesis were suppressed in the L-asparaginase-treated dogs. L-Asparaginase did not affect the antibody response to bovine serum albumin or peripheral blood leukocyte counts. Suppressed antibody responses to sheep RBC and to bovine serum albumin, depressed lymphocyte blastogenesis, and decreased numbers of all peripheral blood leukocytes were seen in dogs given the 3 drugs in combination.

Animals↗
PubMed1982

Salmonellosis in dogs with lymphosarcoma.

In 6 dogs with multicentric lymphosarcoma, salmonellosis developed shortly after the start of anticancer chemotherapy. Three of the dogs died. Signs of illness in those that died were vomiting, diarrhea, neutropenia, anorexia, and fever, usually within 3 days of the start of chemotherapy.

Animals↗
PubMed1982

Lymphocyte blastogenesis in dogs with lymphosarcoma.

Mitogen-stimulated lymphocyte blastogenesis was evaluated, using lymphocytes from 37 dogs with multicentric lymphosarcoma. The majority of the test results was within a normal range, even for those dogs with more advanced disease. However, depressed lymphocyte blastogenesis, when present, almost always occurred in lymphocytes from dogs with clinical stage IV-B and V-B disease. Dogs weighing greater than 25 kg had a significantly (P = 0.04) higher occurrence of clinical stage IV or V disease as compared with dogs weighing less than 15 kg. Dogs with diffuse lymphocytic well-differentiated lymphoma were statistically more likely to be designated clinical stage III at the time of diagnosis, as compared with dogs with diffuse lymphocytic poorly differentiated lymphoma.

Animals↗
PubMed1981

Orientation and configuration of vectorcardiographic QRS loops from normal cats.

The orientations (angles) of mean QRS vectors were manually calculated from scaler orthogonal leads (I, aVf, V10; X, Y, Z) and from X-Y oscilloscope recordings from cats injected with ketamine and acetylpromazine. Those angles calculated from individually recorded leads (I, aVf, and V10) were from cats in right lateral and sternal recumbency. Leads, X, Y, and Z were recorded simultaneously from cats in the sternal recumbency. The oscilloscope recordings were derived from the X, Y, and Z leads. Arithmetic and maximal measurements from ECG scaler leads and maximal and half-area measurements from oscilloscopic recordings were used for calculations. Recordings from 15 cats and from 1 cat 15 times. Based on visual inspection of scattergrams, the X, Y, and Z vectors were not different in orientation from I, aVf, and V10 vectors. Orientation of oscilloscopic vectors were more variable than orientations of vectors calculated from scaler leads. Body position of the cat during recording did not affect mean values of angles derived from leads I, aVf, and V10. Type of measurements did not affect mean values. Variation of orientation was greater among cats than for the intraindividual vector orientations. Configuration and direction of QRS loops from 27 normal cats were also recorded. The greatest variation in loop configuration was in the frontal plane.

Animals↗