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Biomedical subjects

C A Levi D'Ancona

Publications and source records attributed to C A Levi D'Ancona.

4 recordsLinked to original sources
PubMed1991

Experimental studies on BCG in hamsters.

The effects of BCG in the treatment of superficial bladder cancer in man are known, but the mechanism is not quite well understood. Thirty-six hamsters received BCG through three routes: intravesical, intradermal and oral. Each group was composed of 12 animals; BCG was administered to 9 and only saline solution to 3 hamsters. BCG was given once a week for six weeks. The animals were sacrificed at 20, 30 and 65 days after the last administration of BCG. The anatomopathologic study revealed granulomatous reaction in the liver of 5 hamsters and in the spleen of 4 other animals of the intravesical group. In all groups that received BCG, hyperplasia of periarteriolar lymphoid tissue (T zone) of the spleen was observed. We support the view that BCG promotes a systemic reaction whatever the route of administration may be.

Administration, Intravesical↗
PubMed1990

Is routine dilation of the ureter necessary for ureteroscopy?

The results of transurethral ureteroscopic stone removal in 144 patients were reviewed. Patients were treated by two different techniques according to the dilation of the ureterovesical junction before the introduction of the ureteroscope. Group 1 was represented by 71 patients submitted to ureteral dilation and in group 2 there were 73 patients treated without ureteral dilation. There was only one failure in introducing the instrument without ureteral dilation. In patients submitted to transurethral ureteroscopy with previous ureteral dilation, the success of ureteroscopic stone removal was 91.6% and complications occurred in 6.9%, and, in the cases not submitted to ureteral dilation, the success rate was 99.4% and the complication rate 4.1%. The success rate achieved in removing upper third stones was 100.0% middle third 90.5% and lower third stones 95.6%. Of the 144 patients treated, 8 (5.5%) had ureteral injury, but only 1 (0.6%) needed open surgery. We do not believe that ureteral dilation prevents complications or improves the results of ureteroscopic lithotripsy.

Adult↗
PubMed1987

Endourologic approach of ureteral gunshot lesion.

We report a case which demonstrates that to approach an ureteral gunshot lesion endourologically may be an alternative to surgical intervention. We believe that drainage of a damaged ureter should, in selected cases, constitute the first option. This procedure often is successful, but may not be feasible in all cases. We do not believe that simple catheter drainage should replace standard surgical procedures. However, it presents a less invasive treatment alternative which still adheres to conventional surgical principles if a proper patient selection is made.

Adult↗