Biomedical subjects

C A Macedo

Publications and source records attributed to C A Macedo.

13 recordsLinked to original sources

PubMed2000

[Use of Spotorno expansive acetabulum in sequel of acetabular fracture].

A series of 14 total hip arthroplasties using the cementless Spotorno expansive acetabular component was performed to treat post traumatic osteoarthrosis that had developed following an acetabular fracture. The mean age of the patients at the time of the arthroplasty was 47 years (range 28-77 years). This study was performed between 1989 to 1999 (11 years), and the mean follow-up was 4 years and 9 months. Clinical results were evaluated by Merle d'Aubigné and Postel scale, which revealed that 78, 50% of the patients presented good and very good results. The radiological evaluation based on DeLee and Charnley criteria demonstrated a radio-lucent-lin in 3 patients. According to the results obtained in the series the authors concluded that the traumatic acetabular osteoarthrosis can be properly handled with the Spotorno acetabular component when arthroplasty is indicated.

Acetabulum↗

PubMed1999

[Comparation of the antero-lateral and posterior approaches in primary total hip arthroplasty].

Comparison between the antero-lateral and posterior approaches in primary total hip arthroplasty. In this retrospective study, 184 patients were enrolled, 95 submitted to the anterolateral (Watson jones) and 89 to the posterior approach (Moore) from June 1993 to June 1997. The outcomes assessed were perioperative data (operative time, hospital stay, time from surgery until hospital discharge, surgical bleeding and the need for blood transfusion), as well as late complications (deep venous thrombosis DVP, pulmonary embolism, periopheral nerve injury, prothesis instability and others). Both groups did not differ in terms of preoperative parameters. Those submitted to the posterior approach had shorter operative times (p < 0.001), as well as reduced bleeding (p < 0.05) and need for blood transfusion (p < 0.001) during surgery. The outcomes, such as late complications, had similar reduced frequency in both groups. The posterior approach has been successfully applied in our service and proves to be an excellent alternative surgical access to the total hip arthroplasty.

Adult↗

PubMed1990

Differences in heart rate and blood pressure in children with conduct disorder, major depression, and separation anxiety.

Heart rate and blood pressure of children and adolescents admitted to a psychiatric hospital were compared among those diagnosed conduct disorder, major depressive disorder, and separation anxiety disorder. Subjects with conduct disorder had a lower heart rate compared to subjects without a conduct disorder diagnosis; and subjects with separation anxiety disorder had higher heart rate and systolic blood pressure compared to subjects without an anxiety disorder diagnosis. Subjects with major depressive disorder had higher systolic blood pressure than subjects with conduct disorder but no difference in heart rate. The findings are consistent with conduct disorder being associated with decreased noradrenergic function and anxiety/depressive disorder being associated with increased noradrenergic function.

Adolescent↗

PubMed1990

Catecholamines and diagnoses in children.

Theoretically, noradrenergic (NA) function may be lower in subjects with undersocialized conduct disorder (CDU) and higher in subjects with anxiety/depressive disorder. To test this hypothesis, diagnostic and 24-hour urine catecholamine measures were compared between subjects with plasma dopamine-beta-hydroxylase (D beta H) activities less than 6 mumoles/min/L (low D beta H group) and greater than 15 mumoles/min/L (high D beta H group). Several measures relating to norepinephrine metabolism were lower in the low D beta H group, and the low D beta H group had more diagnoses of CDU and fewer anxiety and depressive disorder diagnoses. Comparisons between clinical and biological measures within each of the D beta H groups were also consistent with the hypothesized relationship between NA function, CDU, and anxiety/depressive disorder.

Adolescent↗

PubMed1989

Attention deficit disorder symptoms and urine catecholamines.

The symptoms of hyperactivity, impulsivity, and concentration deficits associated with attention deficit disorder (ADD) may be related, in part, to alterations in dopaminergic and noradrenergic functioning. In this study we correlate the above symptoms with 24-hour urinary catecholamines and their metabolites in emotionally disturbed boys divided into two groups based on their plasma dopamine-beta-hydroxylase (DBH) activities and also divided into the following diagnostic groups: conduct disorder, undersocialized; conduct disorder, socialized; and subjects without conduct disorder. Boys in the low DBH group showed significant correlations between the ADD symptoms and the biochemical measures. The low DBH group may be more genetically homogeneous with regard to catecholamine function, making relationships between catecholamine function and behavior more visible. The group of boys with conduct disorder, socialized had higher 24-hour urinary norepinephrine and vanillylmandelic acid output. The relationship between monoamines and their metabolites appeared to differ among diagnostic groups.

Attention Deficit Disorder with Hyperactivity↗

PubMed1988