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Biomedical subjects

C A Ostrom

Publications and source records attributed to C A Ostrom.

5 recordsLinked to original sources
PubMed1978

Effectiveness of preventive dentistry delivery system.

A preventive dentistry delivery system was developed for maximum effectiveness in private practice. Four new pit or fissure carious lesions developed in 20 patients who were 10 to 20 years old at the start of a two-year exploratory test; there were no new lesions of smooth surfaces. Of the incipient lesions that were under observation, no increase was observed in 23 of 26 pit or fissure lesions, 24 to 25 proximal and all of 26 buccal or lingual smooth surface lesions. In 33 patients 21 to 30 years old at the start of the test, no new lesions appeared and growth of the 142 incipient lesions appeared to be arrested. A low level of gingivitis was maintained in all patients who were tested.

Acidulated Phosphate Fluoride↗
PubMed1977

Combined effects of sucrose and fluoride on experimental caries and on the associated microbial plaque.

In an experimental model, slabs of sound and presoftened bovine enamel were worn in the human mouth for seven days except for periodic removal for in vitro exposure to experimental variables. Supplementation with 3% sucrose for 10 minutes, four times daily for seven days yielded predicted levels of experimental caries. Parallel exposure to 3% sucrose containing 100 ppm fluoride sharply reduced or negated the resultant caries in originally sound enamel, and reversed the simulated pre-experimental caries in most samples of presoftened enamel. Serial layers of test enamel surfaces showed high levels of fluoride accumulated in the originally sound enamel, and even higher levels in the presoftened enamel that had been suppemented with sucrose-fluoride solution. Quantitation of the plaqye microbial flora showed that the fluoride ion exerted no detectable influence. Consistent with the findings in previous studies, some correlation appeared to exist between the degree of experimental caries and that proportion of total plaque that was comprised of S salivarius. S mutans, or lactobacilli.

Adult↗
PubMed1977

Microbial characterization of an experimental cariogenic plaque in man.

Experimentally induced plaque seemed to originate by direct contact inoculation from the vestibular mucosa and saliva. During the next seven days, this plaque developed its own characteristics. Populations of Streptococcus mutans usually less than 2% of total streptococci population in plaques that were less than three days old, increased between days 3 and 7. Proportions of S sanguis, high in early samples, decreased after day 3. Populations of S salivarius, which usually outnumbered other streptococci, fluctuated widely through day 3, and then increased in proportion in subjects who were more productive of experimental caries, but decreased in subjects who were less productive. Proportions of plaque flora comprising lactobacilli paralleled those of S salivarius.

Adolescent↗