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Biomedical subjects

C A Pearson

Publications and source records attributed to C A Pearson.

6 recordsLinked to original sources
PubMed1978

Hypochromia as a clinical sign of tuberculosis in the tropics.

The skin colour of 106 Nigerian tuberculosis patients was measured by colorimetry; and a relative hypochromia, particularly of the face, was found to be associated with tuberculous infection. The hypochromia reached a significant degree compared to a group of 126 control patients with other medical conditions from whom tuberculosis had been excluded. Successful treatment of the tuberculosis resulted in re-pigmentation. It is suggested that relative hypochromia should be included in the list of non-specific signs which may be looked for when considering tuberculosis in the differential diagnosis of chronic cough, and debilitating disease, in the African. The hypochromia of protein-calorie malnutrition was not included in the study, but its importance in relation to coincident tuberculosis is noted. A simple method of measuring skin colour in the consulting room needs to be developed.

Adolescent↗
PubMed1978

Thiacetazone toxicity in the treatment of tuberculosis patients in Nigeria.

In a series of 1,212 tuberculosis patients treated on a regime of streptomycin/isoniazid/thiacetazone (S/INH/thiacetazone) over a period of 10 years in Nigeria there were 171 cases considered to have toxic reactions to thiacetazone (14%). 134 of these (11%) were sufficient to require a change of treatment. Giddiness and rashes were the commonest effects, the former occurring mainly in association with streptomycin, and considered to be largely due to potentiation of streptomycin toxicity by thiacetazone. The advantages of the S/INH/thiacetazone regime in Nigeria are considered to outweigh the disadvantages, so long as necessary precautions are taken to keep the effects of toxicity to a minimum.

Adolescent↗
PubMed1977

Early protected weight bearing in African patients with fractures of the femur.

Among 100 cases of closed fracture of the femur admitted to a Nigerian hospital during the years 1954--71, and treated by skin or skeletal traction, the mean time to clinical union was 6 weeks and to discharge on protected weight bearing 7 weeks. There were no cases on non-union. It is suggested that the traditional recommendation of 12-14 weeks in traction to ensure clinical union of a fracture of the femur should be revised, at least in African patients.

Adolescent↗
PubMed1976

Letter: Rabies.

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Diagnosis, Differential↗