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Biomedical subjects

C A Roobottom

Publications and source records attributed to C A Roobottom.

At least 37 records · Page 2Linked to original sources
PubMed2003

Refined computed tomography of the thoracic aorta: the impact of electrocardiographic assistance.

There have been a number of advances in helical computed tomography (CT) in recent years, which have had a beneficial impact on the quality of imaging of the thoracic aorta. These advances include sub-second gantry rotation, multislice acquisition, and the use of electrocardiographic (ECG) assistance. We examine these techniques with emphasis on the principles behind ECG assistance and its use to reduce aortic motion artefact. We highlight examples of ECG-assisted multislice CT in a spectrum of pathologies of the thoracic aorta.

Aorta, Thoracic↗
PubMed2003

The effect of reporting speed on plain film reporting errors.

AIM: To determine whether reporting plain films at faster rates lead to a deterioration in accuracy. METHODS: Fourteen consultant radiologists were asked to report a total of 90 radiographs in three sets of 30. They reported the first set at the rate they would report normally and the subsequent two sets in two thirds and one half of the original time. The 90 radiographs were the same for each radiologist, however, the order was randomly generated for each. RESULTS: There was no significant difference in overall accuracy for each of the three film sets (p=0.74). Additionally no significant difference in the total number of false-negatives for each film set was detected (p=0.14). However, there was a significant decrease in the number of false-positive reports when the radiologists were asked to report at higher speeds (p=0.003). CONCLUSIONS: When reporting accident and emergency radiographs increasing reporting speed has no overall effect upon accuracy, however, it does lead to less false-positive reports.

Clinical Competence↗
PubMed2003

Three dimensional volume quantification of aortic valve calcification using multislice computed tomography.

OBJECTIVE: To assess a new multislice computed tomography (CT) technique for three dimensional quantification of aortic valve calcification volume (3D AVCV) and to study the relation between stenosis and calcification of the aortic valve. METHODS: 50 patients with echocardiographic calcification of the aortic valve underwent two separate ECG triggered multislice CT for quantification of 3D AVCV. The agreement between the two 3D AVCV scores was assessed and 3D AVCV was compared with echocardiographic markers of severity of aortic stenosis. RESULTS: Overall the level of agreement between the two 3D AVCV scores was excellent (median interscan variability 7.9% (interquartile range 10.1); correlation coefficient, r = 0.99; repeatability coefficient 237.8 mm3 (limits of agreement -393 to 559 mm3)). However, the magnitude of the 3D AVCV did influence the interscan variability. The 3D AVCV correlated closely with the maximal predicted transvalvar gradient (r2 = 0.77) and aortic valve area (r2 = 0.73). CONCLUSIONS: Multislice CT provides a technique for quantifying 3D AVCV that has good reproducibility. There is a close non-linear relation between echocardiographic parameters of severity of valve stenosis and 3D AVCV scores.

Aged↗
PubMed2002

The in vitro and in vivo ultrasonographic appearances of the angio-seal percutaneous closure device.

PURPOSE: To assess the ultrasound appearances of the Angio-Seal device in an animal model and in twenty patients following catheterization of the femoral artery. MATERIALS AND METHODS: Ten patients were scanned within 8 hours of their procedure (early group) and 10 at two to four days (delayed group) using Acuson Aspen and Sequoia scanners. Colour flow images were taken and Doppler spectral analysis was performed proximal proximal to, at and distal to the Angio-Seal device. Early and delayed in vitro images were taken in a water bath in which the Angio-Seal device was deployed across a normal porcine aorta for comparison. RESULT: In the ten early patients colour and Doppler drop out were seen in 100 percent and 90 percent respectively compared with 90 percent and 60 percent in the delayed group. The device was seen in 30 percent and 90 percent in early and delayed groups respectively. In the in vitro study the components of the device were seen and a posterior acustic shadow noted. This shadow was less obvious and the polymer anchor more easily seen in the delayed group. CONCLUSION: The Angio-Seal device produces a consistent artifact when scanned soon after deployment. These appearances could potentially be mistaken for a vascular occlusion by the unwary in the appropriate clinical setting of acute post catheterisation lower limb ischaemia however an awareness of the normal sonographic appearances of this device would make this misinterpretation unlikely.

Absorbable Implants↗
PubMed2002

Multislice computed tomography cardiac imaging: current status.

Non-invasive CT coronary artery imaging has previously had little relevance to most UK radiologists due to the limited availability of electron beam CT scanners. Major advances in CT technology have promoted new applications for helical CT, which include cardiac imaging. Widespread installation of 'multislice' helical CT scanners will make CT coronary artery imaging available for the first time in many UK hospitals. The technical advances and early clinical trial data are reviewed and multislice helical CT cardiac imaging in general is discussed.

Aged↗
PubMed2002

Urgent contrast enhanced computed tomography in the diagnosis of acute bowel infarction.

Bowel infarction commonly presents as an acute abdomen that rapidly progresses to severe shock. The diagnosis is often not clinically suspected. Three cases are described where the diagnosis was made during dynamic contrast enhanced computed tomography (CT), when gas was demonstrated in the portal venous system and liver. Two patients died during surgery, the third survived because of the prompt diagnosis made on CT, and subsequent surgical treatment. The radiological findings are reviewed.

Abdomen, Acute↗
PubMed2002

Aortic valve imaging with computed tomography: a review.

The finding of aortic valve calcification is of clinical relevance. Thickening and calcification of the aortic valve ('aortic sclerosis') may progress over time to calcific aortic stenosis, and calcification of the aortic valve has prognostic importance even in the absence of valve obstruction. Aortic valve calcification may also have effects on the conduction system. There is progressive awareness of the need for an imaging technique that can accurately and reproducibly quantify calcification of native and prosthetic aortic valves. Through adaptation of techniques from electron beam computed tomography (CT) coronary calcium scoring, CT has been proposed as the appropriate imaging modality. Although originally described as a method of comparing the calcification of different aortic valve bioprostheses, the major role suggested for CT aortic valve calcium quantification is now in the field of preventive medicine. This has stemmed from the recognition that traditional vascular risk factors also have a role in the etiology of calcific aortic stenosis. Subsequently, the realization that pharmacological modification of lipid profiles may result in slowing of progression or even regression of aortic valve calcification has led to a need to quantify aortic valve calcification for follow up purposes. Echocardiography has been used to estimate aortic valve calcification in studies of the natural history of aortic stenosis, but it does not accurately quantify calcium. CT appears able to fulfil this requirement, though the technique is still relatively novel. This review examines the need for aortic valve calcium quantification and the evolution of imaging to the current status. Future directions and the promise of new helical CT technologies with respect to cardiac imaging are explored.

Aortic Valve↗
PubMed1998

Long-term follow-up of the antheor inferior vena cava filter.

The first long-term follow-up of the use of the Antheor inferior vena cava (IVC) filter is presented. Between December 1994 and December 1996, 20 Antheor IVC filters were inserted. Seven patients subsequently died and of the 13 patients remaining alive, 11 were available for long-term follow-up. One death was due to migration of the filter to the main pulmonary artery 6 weeks after insertion and because of this case, and other similar reports, the filter has now been withdrawn from clinical use. Of the 11 filters assessed at follow-up, three were fractured. One filter contained thrombus and one IVC was occluded. Our experience highlights the problem of central migration, but also shows a high incidence of filter fracture which has not previously been described with this design of filter.

Adult↗
PubMed1998

Azygos reflux: a CT sign of cardiac tamponade.

Three patients who were investigated with dynamic contrast medium enhanced computed tomography (CT) of the thorax were noted to have pericardial effusions with reflux of contrast medium back along the azygos vein. The diagnosis of cardiac tamponade was not made clinically, but in each case was suggested from the CT findings. Confirmation of the diagnosis was made in all three cases, two patients with echocardiography and one at post mortem. One patient made a rapid recovery following the insertion of a pericardial drain, another made a temporary recovery after pericardiocentesis but the third died. Thirty CT scans performed with similar protocol were reviewed and none of these demonstrated reflux along the azygos vein. The presence of contrast medium refluxing into the azygos vein implies significant haemodynamic disturbance, and in the presence of a pericardial effusion suggests the diagnosis of cardiac tamponade.

Adult↗
PubMed1995

Hepatic venous Doppler waveforms: changes in pregnancy.

A total of 75 fasted healthy normal volunteers were examined during various stages of pregnancy. Examinations were performed in a supine position using an Acuson 128 ultrasound scanner with a 3.5 MHz transducer. Doppler interrogation of the middle hepatic vein was made during quiet respiration by one of three examiners. The Doppler waveforms were subsequently assessed blindly by one of the authors and categorized as normal, damped, or flat. Between 12 and 20 weeks, the majority of patients had normal hepatic pulsatility (64%) with 20% damped and 16% flat. Between 20 and 30 weeks there was a significant change (p > 0.001) with 68% being flat, 20% damped, and only 12% normal. In the last 10 weeks of pregnancy the changes were more marked: 80% were flat, 12% dampened, and 8% normal. There was a profound change in hepatic venous pulsatility during pregnancy. Hepatic waveforms changed from their normal pulsatile nature to become completely flat with increasing gestation. These changes were more frequent and more marked the further gestation progressed.

Adult↗