Biomedical subjects
C A Sheldon
Publications and source records attributed to C A Sheldon.
Bilateral renal vein thrombosis in infancy and childhood.
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Peripheral postcapillary venous pressure--a new hemodynamic monitoring parameter.
Peripheral postcapillary venous pressure (PCVP) appears to be an indicator of peripheral perfusion (cutaneous blood flow) in the experimental animal. Eighteen male mongrel dogs under balanced anesthesia were subjected to either slow, continuous hemorrhage 0.65 ml/kg/min) or plasma expansion with dextran 40 (0.80 ml/kg/min) over a period of 1 hour. Peripheral PCVP, cental venous pressure arterial pressure, cardiac output (CO), mixed venous oxygen saturation, pulmonary arterial pressure, and pulmonary wedge pressure were monitored on a continuous basis. The only parameter that consistently gave a predictable measure of the degree of induced volume change without requiring pulmonary arterial catheterization was PCVP. PCVP showed a close correlation with CO (r = 0.96).
Urologic evaluation and treatment of the myelodysplastic child.
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Obstructive uropathy, renal failure, and sepsis in the neonate--a surgical emergency.
Two infants who had obstructive uropathy accompanied by renal failure and sepsis are reported herein. Diagnostic and therapeutic techniques used to treat this type of surgical emergency are discussed in the order they were performed, as follows: (1) resuscitation for severe fluid and electrolyte disturbances; (2) gathering of cultures and initiation of antibiotic therapy; (3) the decision of whether or not dialysis is required, as well as when and how diagnostic evaluation should proceed; (4) the decision of whether dialysis is necessary or whether correction of obstructive uropathy can begin; and (5) the choice of the best operative procedure for this individual. This article emphasizes the necessity for a multidisciplinary team approach to these patients.
Incidental carcinoma of the prostate: a review of the literature and critical reappraisal of classification.
The problem in treating incidental carcinoma of the prostate is that of distinguishing between tumors that will have a long, benign natural history and those that will progress rapidly. A review of the English literature concerning incidental prostatic carcinoma reveals that patients with focal low grade tumors have a good prognosis, while patients with high grade lesions often suffer rapid tumor progression. By contrast, the clinical significance of high volume, low grade tumor is unknown. A method has been developed to evaluate the distribution of prostatic cancer using 4-quadrant transurethral prostatic resection. A detailed method for staging these cancers based on a comprehensive, segmental histopathological analysis also is presented. A precise definition of the stages of prostatic cancer should eventually improve our understanding of the natural history of this disease.
Scanning electron microscopy of fetal and neonatal lamb cardiac cells.
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Diagnostic imaging for pediatric scrotal disorders.
Classification of pediatric scrotal disorders into three typical clinical manifestations--acute scrotal disorders, scrotal masses, and cryptorchidism--provides a practical basis for evaluation with the most commonly used modalities--sonography, scintigraphy, and magnetic resonance (MR) imaging. Acute scrotal disorders of children include acute epididymitis, torsion of an appendix testis or appendix epididymis, and torsion of the spermatic cord. Either scintigraphy or sonography may be used as the first imaging study, and both can aid in distinguishing among the disorders to different degrees. However, sonography is becoming the preferred modality, primarily because of the superior anatomic detail provided. Scrotal masses are also best depicted with sonography, although MR imaging can occasionally be a useful adjunctive modality. In cases of suspected cryptorchidism with equivocal clinical findings, both sonography and MR imaging may be useful, although sonography is usually the initial study. Knowledge of characteristic imaging appearances, as well as benefits and limitations of the available modalities, enables appropriate, expeditious radiologic evaluation of pediatric scrotal disorders.
Advantages of automating vital signs measurement.
A comparison of automated versus conventional vital signs measurement methods revealed that the automated method required significantly less time and was perceived by nursing staff to be easy to use, accurate, and superior to the conventional method.