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Biomedical subjects

C A Speed

Publications and source records attributed to C A Speed.

27 records · Page 2Linked to original sources
PubMed1998

Stress fractures.

Stress fractures are being increasingly reported as a common cause of morbidity in both healthy populations and those with underlying diseases involving abnormal bone. An insight into the types and pathogenesis of stress fractures is necessary to considering the diagnosis, management and prevention of such conditions. The classification, aetiology and aspects of management are discussed.

Fractures, Stress↗
PubMed1996

Coincident seronegative spondarthritis: a case report.

A patient is described in whom ankylosing spondylitis (AS) and reactive arthritis (ReA) coincided. Follow-up five years later showed no progression of his AS. He demonstrates that some individuals do have the capacity to express seronegative spondarthritides in different ways, possibly dependent on the infective trigger. The lack of long term effect of the second disease is both clinically reassuring and theoretically intriguing.

Adult↗
PubMed1996

Simultaneous bilateral tibial stress fractures in a 15-year-old milkman--a case report.

Although stress fractures are well recognized, their frequency, sequelae and complex aetiology are often under-rated. In this case report, we describe an unusual case of simultaneous bilateral stress fractures of the proximal tibial shaft in a young man, exposed to a sudden increase in unaccustomed joint loading due to his part-time occupation. The pathogenesis is discussed.

Adolescent↗
PubMed1996

Ultrasound velocity and attenuation at different skeletal sites compared with bone mineral density measured using dual energy X-ray absorptiometry.

Measurements of ultrasound velocity were performed in the tibia in a group of 89 female subjects (mean age 50.6 years). Velocity and broadband ultrasound attenuation (BUA) measurements were performed in the os-calcis in a group of 100 male and female subjects (mean age 55.8 years). Dual energy X-ray absorptiometry (DEXA) scans were also performed on all of these subjects enabling measurements of lumbar spine and femoral neck bone mineral density (BMD) to be obtained. In two small subgroups of the above groups, each comprising 20 subjects, measurements of tibial BMD and os-calcis BMD were also performed. Tibial BMD and ultrasound velocity were found to be well correlated (r = 0.71), although both spine and femoral neck BMD were poorly correlated with ultrasound velocity in the tibia (r = 0.299 and 0.072, respectively). BUA of the os-calcis was moderately correlated with BMD at the same site (r = 0.44) and showed similar or slightly better correlations with BMD measurements of the lumbar spine and femoral neck (r = 0.410 and 0.537, respectively). Ultrasound velocity in the os-calcis was well correlated with os-calcis BMD (r = 0.729) but only moderately correlated with spine and femoral neck BMD (r = 0.470 and 0.498, respectively). This study suggests that BUA and ultrasound velocity measurements of the os-calcis are better predictors of BMD at the critical skeletal sites of the lumbar spine and femoral neck than ultrasound velocity in the tibia. Ultrasound velocity in the tibia and the os-calcis was found to be a good predictor of the BMD in the measured bone.

Absorptiometry, Photon↗
PubMed1995

Polymyalgia rheumatica, temporal arteritis and malignancy.

The use of steroid therapy in polymyalgia rheumatica and temporal arteritis is necessary and usually effective, but may mask coexisting disease. The importance of early consideration of other disorders in such patients is illustrated by three case histories.

Adenocarcinoma↗
PubMed1994

Non-steroidal anti-inflammatory induced diaphragm disease of the small intestine: complexities of diagnosis and management.

A 52-yr-old lady with RA on long term NSAIDs developed an iron-deficiency anaemia and subsequently presented with subacute intestinal obstruction. After intensive investigation, a diagnosis of diaphragm disease of the small intestine was made at laparotomy. The features of diaphragm disease and the difficulties with diagnosis and management of the condition are discussed.

Adult↗