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Biomedical subjects

C Abdelkhirane

Publications and source records attributed to C Abdelkhirane.

4 recordsLinked to original sources

[Value of end diastolic pulmonary venous flow in the estimation of left ventricular diastolic pressure].

The aim of this study was to analyse the possible relationship between inversion of the end diastolic wave of pulmonary venous flow (Avp) recorded by transoesophageal echocardiography in the left superior pulmonary vein and left ventricular end-diastolic pressures (LVEDP) at cardiac catheterisation. In this series of patients, there was a poor correlation between the E/A ratio of transmitral blood flow and LVEDP. On the other hand, there was a better correlation between LVEDP and the difference of duration of the end diastolic Avp wave and the A wave of mitral flow. An even better correlation was found between LVEDP with respect to the contribution of atrial systole and the difference of duration Avp-A. When the pressure due to atrial contraction exceeds 15 mmHg, the difference between the durations of pulmonary and mitral A waves increases. Therefore, when the duration of the end diastolic Avp is greater than that of the mitral A wave, a LVEDP of over 15 mmHg may be predicted with a sensitivity of 88% and a specificity of 74%.

Adult↗

[Relative value of attenuation and negativation of systolic pulmonary venous flow in severe mitral insufficiency. Transesophageal echocardiographic study].

The aim of this study was to analyse the velocity profile of the systolic fraction of the pulmonary venous flow (PVF) in mitral regurgitation (MR). Three velocity profiles were identified in left superior pulmonary vein. Inversion of the systolic fraction of the PVF was specific for angiographic grade 4 MR (specificity 97%, sensitivity 100%). On the other hand, a decrease in this wave is much less specific for mild MR and depends on severe factors such as left atrial pressure, size and ejection fraction and the lack of atrial systole (as in atrial fibrillation or atrioventricular block). Therefore, inversion of PVF has a good positive predictive value for severe MR, but the interpretation of attenuation of this wave should take into consideration not only the MR but also left atrial pressure and compliance.

Blood Flow Velocity↗

[Low calcium channel inhibitors: modalities for use].

The recent discovery of numerous new "calcium inhibiting" molecules and the multiplicity of their indications in cardiology and in other specialties have made it necessary to clarify their position in the armory of medical treatments in cardiology and their associations with other treatments. Before describing the various protocols for the use of calcium channel inhibitors, the article describes the basic factors involved in the choice of the most appropriate calcium channel inhibitor on the basis of their mechanisms of action, the tissue selectivity, the pharmacokinetic profile and the formulations available.

Calcium↗

Diagnosis of ruptured sinus of Valsalva aneurysms: potential value of transesophageal echocardiography.

Two patient cases are reported in which an aneurysm of the right coronary sinus of Valsalva ruptured into the right ventricular outflow tract, near the crux of the heart. Transthoracic two-dimensional echocardiography and transesophageal echocardiography using Doppler color flow mapping allowed accurate preoperative assessment of the left-to-right shunt, which was subsequently confirmed by contrast aortography and surgery.

Aortic Rupture↗