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C Abood

Publications and source records attributed to C Abood.

4 recordsLinked to original sources

Disc herniation at T1-2. Report of four cases and literature review.

In preparing this paper, the authors reviewed their experiences with four cases of T1-2 disc herniation as well as the medical literature on the subject. Intervertebral thoracic disc herniations are uncommon and high thoracic disc herniations are rare. In the upper third of the thoracic spine, T1-2 is the most common level for disc ruptures. Four cases of disc herniation at T1-2 that caused T-1 radiculopathy are reported in this paper. In reviewing the literature on thoracic disc herniation, the authors found 27 cases at the T1-2 level, 23 of which were lateral disc herniations that produced radiculopathy and four of which were central disc herniations that caused myelopathy. The clinical signs and symptoms of T-1 radiculopathy are similar to those of C-8 radiculopathy; however, distinguishing features can frequently be found on neurological examination. The T-1 radiculopathy usually involves weakness of the intrinsic muscles of the hand. The motor deficit of C-8 radiculopathy involves the intrinsic muscles of the hand and most of the flexors and extensors of the fingers and wrist. The T-1 radiculopathy may produce Horner's syndrome (oculosympathetic paralysis) and diminished sensation in the axilla, which are not found with C-8 radiculopathy. In clinical presentation as well as in treatment, the lateral T1-2 disc herniation resembles a cervical disc herniation, whereas the central T1-2 disc herniation displays the usual appearance of a thoracic disc herniation.

Aged↗

Regional ischemia during cerebral bypass surgery.

BACKGROUND: We evaluated brain tissue oxygen pressure (PO2), carbon dioxide pressure (PCO2), and pH during regional ischemia produced by temporary brain artery occlusion. METHODS: This 45-year-old woman with cerebral occlusive disease was scheduled for right superficial temporal artery (STA) to middle cerebral artery (MCA) bypass. Two Paratrend 7 sensors measuring PO2, PCO2, and pH were inserted into the cortex in the distribution of the MCA at a distance of 1 cm from each other. Jugular bulb oxygen saturation was measured by oximetry. Local perfusion was measured with a flow probe on the MCA and using a laser Doppler. Tissue responses were recorded during: (1) 100% oxygen ventilation, (2) hypercapnia, and (3) an 18 minute occlusion of the right MCA. RESULTS: Under baseline conditions, tissue PO2, PCO2, and pH suggested that ischemia was present in tissue measured by both sensors. Tissue PO2 rose 40%-50% in both regions during 100% oxygen ventilation. During hypercapnia, blood flow increased in the MCA, but local perfusion did not increase in region 2. During temporary occlusion of the MCA, ischemic changes in PO2, PCO2, and pH were seen in region 2 but not in region 1. Local perfusion decreased 80% in region 2, where ischemic changes were seen. CONCLUSIONS: These results show that changes in tissue PO2, PCO2, and pH are consistent with local perfusion. The use of multiple tissue sensors can detect the presence of watershed ischemia that is not demonstrated by jugular bulb measurement.

Brain↗

Brain tissue response to CO2 in patients with arteriovenous malformation.

We tested whether cerebral arteriovenous malformations (AVM) alter brain tissue oxygen pressure, PO2, carbon dioxide pressure PCO2, and pH before, during, and after hypercapnia. A craniotomy was performed and a sensor inserted into normal brain tissue (control) (n = 7) or into tissue adjacent to an AVM (n = 9). Under baseline conditions, tissue PO2 was 80% lower in AVM compared to control patients, but PCO2 and pH were normal. During a 10 mm Hg increase in PaCO2, tissue PO2 increased only in AVM patients, PCO2 increased in both groups, and pH decreased only in controls. When hypercapnia was reversed, tissue PCO2 decreased below baseline and pH increased in AVM patients. Results suggest that tissue CO2 washout and elevated pH result from increases in blood flow during hypercapnia. This response may be related to symptoms of hyperperfusion during AVM resection.

Brain↗