Depression and somatic comorbidity.
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Chronic Disease↗
Biomedical subjects
C Alberque
Publications and source records attributed to C Alberque.
Chronic pain presenting as major depression in a cross-cultural setting.
We report on a female African immigrant who developed chronic pain as a consequence of osteomalacia. Due to cultural particularities in pain expression, her symptoms were first attributed to a major depressive episode. Cultural factors influencing pain perception and expression are reviewed. The importance of working with competent interpreters in cross-cultural settings is emphasized.
Attitude to Health↗
Olanzapine-induced neuroleptic malignant syndrome.
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Adult↗
Left temporal rhythmic electrical activity: a correlate for psychosis? A case report.
It is well recognized that epileptic patients are at higher risk for acute or chronic psychotic states than non-epileptic subjects. Here we present intracranial depth electrode recordings during a psychotic episode in a 20-year-old woman who was referred for presurgical evaluation. Unrelated to her seizures, she presented acoustic hallucinations and delusions and became agitated for a duration of 18-24 hours. During this period, a new unusual pattern of sharp slow waves was seen semi-rhythmically every 2-3 sec from left anterior neocortical temporal areas. Her condition responded well to a treatment with Haloperidol, but not with Benzodiazepines. Ictal and interictal scalp- and depth-EEG recordings outside the psychotic episode as well as MRI-based volumetry, PET, SPECT and neuropsychological testing gave evidence of bilateral temporal and frontal dysfunction. This case report suggests that psychosis in epileptic patients may be based on a bilateral cerebral dysfunction linked together in a pathological network, but with a focal (here: left temporal) driving mechanism.
Adult↗