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Biomedical subjects

C Alexandridis

Publications and source records attributed to C Alexandridis.

At least 19 recordsLinked to original sources
PubMed2005

Gingival fibromatosis and significant tooth eruption delay in an 11-year-old male: a 30-month follow-up.

This case report describes the dental management of an unusual case of idiopathic gingival fibromatosis with multiple impacted primary teeth, and the absence of eruption of permanent teeth, in an 11-year-old boy and at the 30-month follow-up. The patient presented with severely enlarged gingival tissues affecting both arches and multiple retained and non-erupted primary teeth. He had already been subjected to localized gingivectomies at the ages of 7 and 9 years. He had no known syndrome and there was no family history of any similar disorder. The patient was treated under general anaesthesia to remove the excessive gingival tissues using apically positioned flaps. During the surgical procedure, over-retained and unerupted impacted primary teeth were extracted in order to facilitate the eruption of the permanent successors. Two years postoperatively, there was no recurrence of the gingival enlargement. Overdentures were then constructed because none of the permanent teeth had yet erupted. Furthermore, pre-eruptive coronal resorption was detected radiographically affecting the crown of the unerupted 36. Thirty months postoperatively, no recurrence of gingival enlargement was seen, but the permanent teeth had still not erupted.

Anodontia↗
PubMed2000

Epidermal nevus syndrome with development of a mandibular ameloblastoma.

Epidermal nevus syndrome (ENS) is a hamartoneoplastic syndrome characterized by the association of epidermal nevi with abnormalities in other organ systems. We report a 32-year-old woman with ENS that, in addition to cutaneous manifestations, showed red plaques on the maxillary and mandibular labial alveolar mucosa and a papillomatous lesion of the midline posterior hard palate. Radiographic examination of the jaws was noncontributory. Approximately 5 years later, a follicular ameloblastoma developed in the mandible. The tumor showed duct-like cystic spaces, continuity with the overlying epithelium, and globular myxomatous areas in the connective tissue. The palatal lesion was diagnosed as papilloma, whereas the maxillary plaques showed nonspecific mucositis. The association of ameloblastoma with ENS is discussed. This is the second case of ENS associated with ameloblastoma reported in the medical literature.

Adult↗
PubMed1991

A new endodontic stabilizer implant device.

A new endodontic stabilizer implant device is presented that can be used immediately after enucleation of large periapical cysts. The force transmission characteristics of this implant were evaluated by means of photoelasticity. The implant served to distribute incisal forces within the supporting structure. Improved stress conditions resulted at the tooth apex and between the apex and the superior border of the implant when the tooth was subjected to apicoectomy.

Apicoectomy↗
PubMed1991

Functional stress modification after high condylectomy surgery.

Surgical removal of the head of the condyles inevitably leads to radical redistribution of loads applied to the mandible. The nature of this redistribution can have important implications on the surgical approach and subsequent reconstructive procedures. The purpose of this investigation was to visualize photoelastically the functionally delivered stresses after high condylectomy surgery. Three identical models of a dentate human mandible were constructed from a photoelastic material. One mandible simulated a unilateral and the other simulated a bilateral high condylectomy. The third mandible had both condyles intact and served as basis for comparisons. Silicone implants were placed on the sectioned condylar heads. The condyles, with the silicone implants, were fitted into simulated fossae and the mandibles were loaded unilaterally and bilaterally. The resulting stresses were observed and photographed in the field of a circular polariscope. Substantial differences in load-generated stresses were observed as a result of both unilateral and bilateral condylectomies, compared to the normal case. The most severe stress conditions occurred with the unilateral condylectomy, where stresses associated with torsion were most evident.

Humans↗
PubMed1985

Distribution of stresses in the human skull.

A three-dimensional photoelastic model was reproduced from a human skull. The insertions of the superficial and deep portions of the masseter muscle, the temporalis muscle, the medial pterygoid muscle and the temporalis fascia were simulated with leather bonded to the appropriate areas. The following loading conditions were employed: (i) all three muscles were bilaterally loaded without occlusal loads; (ii) all three muscles were bilaterally loaded while occlusal loads were simultaneously applied on the maxillary teeth. The stress freezing technique was used to lock the resulting stress patterns into the model skull. The stress trajectories were observed and photographed in a circular polariscope. The mandibular closing muscles and the occlusal loads produced stresses which progressed through the maxilla, following a nasal, a zygomatic and a pterygoid route, while stress concentrations were seen in the frontonasal, zygomaticomaxillary and the pterygopalatine sutures. In the malar bone area the stresses were seen to branch superiorly to the frontozygomatic suture and posteriorly along the zygomatic arch to the zygomaticotemporal suture and the temporal bone. Generally, the stresses were concentrated in those areas of the skull where architectural reinforcement had been demonstrated by other methods.

Bite Force↗
PubMed1984

Periodontal ligament changes in patients with progressive systemic sclerosis.

Progressive systemic sclerosis (PSS) is a generalized collagen disease which has oral manifestations, including widening of the periodontal ligament (PDL) space. The purpose of this study was to measure the extent of thickening of the PDL space in a group of 26 patients with PSS and in a similar group of age and sex-matched control patients. The width of the PDL was measured from periapical radiographs at four sites around seven selected teeth for every patient. The mean PDL width was found to be larger in all the patients with PSS than in the control patients, around both anterior and posterior teeth. One third of the teeth of patients with PSS had PDL widths thicker than the range observed in the control patients. When average thickness of PDL widths for each patient is compared, at least 65% of the patients with PSS have mean PDL widths which are greater than the range for control patients. The increased thickness of the PDL space associated with PSS is more pronounced in posterior teeth than in anterior teeth.

Adult↗
PubMed1981

Distribution of stress patterns in the human zygomatic arch and bone.

A three-dimensional photoelastic model was reproduced from a human skull. The insertions of the superficial and deep portions of the masseter muscle and the temporalis fascia were simulated with leather bonded to the appropriate areas. The following loading conditions were employed: (1) bilateral loading of the masseter muscle; and (2) bilateral loading of the masseter muscle together with a bilateral occlusal load. Ther stress freezing technique was used to lock the resulting stress patterns into the model skull. The stress trajectories were observed and photographed in a circular polariscope. The results suggest that the major stress trajectories to the zygomatic bone and arch follow an alveolo-maxillary-zygomatic-temporal direction. Stresses were highly concentrated in the zygomatic process of the temporal bone. Generally, the stresses were concentrated in those areas of the bone where architectural reinforcement had been demonstrated by other methods.

Dental Occlusion↗