Serum lipids and arterial blood pressure in relation to waist-to-hip ratio in young males.
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Adolescent↗
Biomedical subjects
C Aliferis
Publications and source records attributed to C Aliferis.
Data explorer: a prototype expert system for statistical analysis.
The inadequate analysis of medical research data, due mainly to the unavailability of local statistical expertise, seriously jeopardizes the quality of new medical knowledge. Data Explorer is a prototype Expert System that builds on the versatility and power of existing statistical software, to provide automatic analyses and interpretation of medical data. The system draws much of its power by using belief network methods in place of more traditional, but difficult to automate, classical multivariate statistical techniques. Data Explorer identifies statistically significant relationships among variables, and using power-size analysis, belief network inference/learning and various explanatory techniques helps the user understand the importance of the findings. Finally the system can be used as a tool for the automatic development of predictive/diagnostic models from patient databases.
Artificial Intelligence↗
Are adrenal and testicular androgen levels correlated?
To investigate the reported correlation between adrenal and testicular serum androgen levels, testosterone, DHEAS and androstenedione were measured in the serum of 92 healthy young males. Testosterone and androstenedione were found to have a weak but statistically significant correlation, while no correlation existed between testosterone and DHEAS, or DHEAS and androstenedione. These results indicate that although common steroidogenic pathways lead to androgen synthesis in both adrenals and testes, the regulation of steroid production in these glands is influenced by different factors. The correlation of testosterone with androstenedione can be attributed to their peripheral interconversion as well as to the fact that half of androstenedione is of testicular origin. Various other aspects of the androgen regulation mechanism such as ACTH stimulation and the role of aging, are presented and discussed.
Adolescent↗
Incidence of gynaecomastia in 954 young males and its relationship to somatometric parameters.
The incidence of gynaecomastia was evaluated in 954 healthy young men aged 18-26 years, and was correlated with several somatometric parameters (height, weight, testes size, eye colour, scalp hair colour, scalp hair density, acne, density and extent of body hair). Gynaecomastia (> 2 cm breast tissue) was found in 40.5% (bilateral 85%, left 7.8%, right 7.2%) of the subjects. Highly statistically significant differences were found between subjects with or without gynaecomastia in their weight (79.7 +/- 10.7 kg versus 69.1 +/- 7.8 kg respectively; p < 0.001) and in their body hair (subjects with gynaecomastia had more dense and extensive body hair than those without; p < 0.001). When the density and extent of body hair was analysed separately for each age, it was found that subjects with gynaecomastia had completed the development of body hair earlier, since 80% of them had completed their body hair by the age of 23 years versus only 45% of those without gynaecomastia. This observation leads to the assumption that obesity and/or an earlier maturation of the subjects with gynaecomastia may play a role in the development of breast tissue, although the possibility of an increased tissue sensitivity to hormonal action cannot be excluded.
Adolescent↗