Infection with E.B. virus and rheumatoid arthritis.
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Biomedical subjects
Publications and source records attributed to C Allen.
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By a multiple extraction procedure the unesterified fatty acids of skim milk have been shown in at least three entities: a) free dissociated and undissociated fatty acids, b) fatty acids associated with the membrane material in skim milk, and c) fatty acids of unknown origin requiring acidification to pH 1.5 for extraction.
Photodegradation of riboflavin in 50-ml samples of fluid milks exposed to fluorescent light (2690 lux) followed first-order reaction kinetics, and the reaction rate (s-1) averaged 1.86 x 10(-5) in skim milk and 1.47 x 10(-5) in whole milk. Additional evidence led us to conclude that photodegradation of riboflavin proceeds prior to the appearance of a light-induced off-flavor.
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Because vasopressin is one of the most potent naturally occurring pressor agents, and because of its importance in the regulation of blood volume and composition, we have undertaken a study of the role of vasopressin in the pathogenesis of the hypertension in the Okamoto-Aoki spontaneously hypertension (SH) rat. In SH rats, systolic blood pressure increased from 135 +/- 3 (SE) mmHg at age 33 days to 184 +/- 3 mmHg at age 75 days (P less than 0.01). In the Wistar-Kyoto (WKY) control rats, blood pressure increased from 100 +/- 2 to 120 +/- 2 mmHg (P less than 0.01). The differences in blood pressure between the SH and WKY rats at all ages were significant (P less than 0.01). During the age period 33-75 days, the 24-h urinary excretion of vasopressin in the SH rat was consistently more than twofold greater (P less than 0.01) than in the WKY rat. Plasma vasopressin concentration and pituitary vasopressin content were also elevated in the SH rat (P less than 0.01 and P less than 0.02, respectively). Changes in systolic blood pressure in the SH rat, however, were not paralleled by changes in the urinary excretion of vasopressin. The data indicate that the secretion of vasopressin is elevated in the SH rat. However, the magnitude of this elevation, in and of itself, may not be sufficient to account for the rising blood pressure in the young SH rat.
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Fifty-five soldiers have been observed over a vigorous 10-day sledging patrol in the Canadian arctic and subarctic. Initial observations showed a low level of physical fitness (26% body fat, aerobic power 41.9 +/- 7.8 ml kg-1 min-1, handgrip force 43.7 +/- 7.2 kg). Over 2-week northern sojourn, energy expenditures as measured by a Kofranyi-Michaelis respirometer and diary observation averaged 3248 kcal (13.6 MJ) day-1, with a small (152 kcal (633 kJ)) positive daily energy balance. A weight loss of 1 kg, presumably water, was made good within 1 week of return to the south. A fat loss of some 3.9 kg was probably attributable largely to the demands of lean tissue synthesis. The lean mass was increased by 3.9 kg over the trial, with parallel gains of muscle force and aerobic power. The rapid mobilization of depot fat led to marked ketonuria.
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