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Biomedical subjects

C Amoroso

Publications and source records attributed to C Amoroso.

12 recordsLinked to original sources

Preoperative sonographic features of borderline ovarian tumors.

OBJECTIVE: To determine the sonographic findings that distinguish borderline ovarian tumors (BOT) from both benign and invasive malignant tumors, thus allowing conservative treatment and laparoscopic management of these tumors. METHODS: We reviewed retrospectively transvaginal sonograms of 33 women who, when evaluated further by surgery and histology, were found to have BOT. Twenty-three were premenopausal and 10 were postmenopausal (mean age +/- SD, 45.8 +/- 15.7 years). For each mass, size and morphological features and power Doppler characteristics were evaluated. We compared these findings with those of 337 patients with benign ovarian tumors and those of 82 patients with invasive malignant ovarian tumors. Patients with dermoid cysts were not included in the study. RESULTS: Of the 33 BOT, 15 were mucinous and 18 were serous cystadenomas. The presence of papillae, defined as a small number of solid tissue projections, 1-15 mm in height and 1-10 mm in width (base) and length (base), into the cyst cavity from the cyst wall, was significantly more frequent in BOT (48%) than it was in benign (4%) and invasive (4%) malignant tumors. Intracystic solid tissue (> 15 mm in height or > 10 mm in width or length) was observed in 48% of invasive malignant masses but in only 18% of BOT and in 7% of benign tumors (P < 0.001). No sonographically unilocular, hypoechoic, smooth-walled adnexal cysts were invasively malignant but three unilocular cysts with a diameter of > 6 cm were serous BOT. Although close attention was paid to the cyst wall at ultrasound examination we did not observe in these three cysts the very small papillae which were found at histological analysis. CONCLUSIONS: The most frequent diagnostic feature on imaging BOT is the presence of papillae within the cyst. However, neither papillae nor other sonographic features constituted highly sensitive sonographic markers of BOT.

Adenocarcinoma, Mucinous↗

Eccrine spiradenoma of the ear: case report.

A case of eccrine spiradenoma of the left pinna is described. To the best of our knowledge, this is the first report regarding this site. The treatment was a surgical excision in safe margins. This rare benign tumour should be considered for the differential diagnosis of solitary or multiple soft tissue lesions of the head and neck.

Adenoma, Sweat Gland↗

Hearing loss evaluation of Sjögren's syndrome using distortion product otoacoustic emissions.

Sjögren's syndrome (SS) is a cell-mediated immune disorder primarily affecting the exocrine glands and hearing loss may be the first otological manifestation of this autoimmune disease. In order to assess the degree of sensorineural hearing loss in SS, 22 female patients were examined by means of standard audiometric tests (pure-tone audiometry, acoustic reflexes and impedance testing) and using distortion product otoacoustic emissions (DPOAEs). The results indicated that only 36.3% of the patients had mild sensorineural hearing loss. Hearing level and distortion product threshold estimates were found to be significantly correlated. No relationship was found between the duration of the disease and the DPOAE and hearing threshold variables. The data suggest that SS may not directly cause sensorineural hearing loss.

Adult↗

Mucoceles of the frontal sinus. Clinical and therapeutical considerations.

BACKGROUND: Mucocele is an epithelial lined mucus-containing sac completely filling a paranasal sinus and capable of expansion by virtue of a dynamic process of bone resorption and new bone formation. It is the most common lesion causing expansion of the paranasal sinuses. Even though mucoceles of paranasal sinuses are increasingly treated by endoscopic surgery, the external approach with or without the obliteration of the sinus still remains a useful and sometimes the only tool in the treatment of this disease. METHODS: The results obtained in seven patients observed at the ENT Department of the University of Ferrara (Italy) in the period ranging from 1989 to 1999 are presented; they were affected by massive fronto-ethmoidal mucoceles and treated with the external approach alone or combined with an endonasal approach and osteoplastic flap. They were five males and two females, with a mean age of 56.5 years. Locations were bilateral in one mucocele, while in six patients only one side was involved, with a prevalence of the left frontal sinus (4:2). RESULTS: No patient showed any local or general complication in the postoperative period. The follow-up showed no recurrence of the disease. CONCLUSIONS: Since the osteoplastic flap was introduced one hundred years ago, it still remains the optimal surgical treatment for fronto-ethmoidal mucoceles. Even though, today, endoscopic surgery represents the new horizon in the management of the sinonasal disease, mucoceles need a surgical treatment which allows the total vision of the cavity to obtain radical treatment and any recurrence of disease.

Aged↗

[A case of temporal arteritis presenting with sensorineural hearing loss].

The inflammatory lesions in giant cell arteritis involve the cranial branches of the arteries originating from the arch of the aorta most prominently. The vessels are thickened tender, and nodular with absent or reduced pulsation. In literature sensorineural hearing loss and Horton's arteritis are rarely associated. A case of temporal arteritis presenting with sensorineural hearing loss is described.

Aged↗

Clinical and radiological findings in subjects with unilateral Ménière's disorder.

In order to contribute to the knowledge of the possible causes of Ménière's disorder, the authors have conducted systematic studies based on blood analysis and on petrous bone radiological examinations in patients suffering from unilateral Ménière's disorder and in two control groups, one of patients with unilateral sudden sensorineural deafness and the other one of normally hearing subjects suffering from neurological diseases. Blood tests have revealed systemic disorders (dyslipidosis, hypoglycaemia, hyperglycaemia, hypothyroidism lues) in 49%, 48% and in 50% of the subjects respectively with Ménière's disorder, with sudden deafness, and with normal hearing. As to the radiological study, changes of the temporal bone (absence or small cells pneumatization and/or absence or narrowing of the vestibular aqueduct) were found in 78% of ears with Ménière's disorder, in 34% of ears with sudden deafness and in 46% of normal ears.

Adolescent↗

Clinical experience with remote masking.

Remote masking (RM) consists of a rise of the threshold for low-pitched tones when the ear is exposed to a high-frequency noise band delivered with high intensity. This phenomenon has been attributed to mechanical non-linear distortion of the cochlear partition, as an effect of the envelope of a non-uniform signal. The authors studied RM in patients suffering from unilateral Menière's disorder, acoustic neuromata, other sensorineural lesions and presbyacusis. The behaviour of RM in the different experimental groups shows that the RM value is normal in acoustic neuromata; it is variable and not related to the severity of the hearing loss in sensorineural losses, and it is reduced in the affected ear in patients suffering from Menière's disorder. Finally, RM is reduced as a function of ageing, progressively and symmetrically in both ears in presbyacusic subjects. The results of the research seem to confirm the hypothesis that RM may be due to mechanical effects in the inner ear and suggest the possibility of using RM as a test of cochlear partition rigidity.

Adolescent↗

[Acoustic reflexometry in presbyacusis (author's transl)].

The authors have studied the relations between crossed and uncrossed acoustic stapedius reflex thresholds in presbyacusic subjects in order to verify whether ageing produces brain stem auditory lesions. The results showed in 55% of the presbyacusics a brain stem disorder characterized by the absence of one, several or all the acoustic reflexes; very often there was only an abnormal difference between crossed and uncrossed acoustic reflex thresholds.

Acoustic Impedance Tests↗

Remote masking in presbycusis.

Remote Masking (RM) (a rise in threshold for low-frequency tones when the ear is exposed to a high intensity noise band of high frequency) has been attributed to mechanical nonlinear distortion of the cochlear partition, as an effect of the envelope of a nonuniform signal. Clinical studies using RM have revealed RM is normal only when both the endolabyrinthine pressure and the cochlear hydrodynamics are normal. Increasing the stiffness of the cochlear partition affects adversely the mechanism of motion of the cochlear duct and reduces RM values. We studied RM in normal young Ss and in patients with presbycusis in order to determine whether aging of the inner ear also induces stiffness of the cochlear partition. In presbycusic Ss the RM values were indeed reduced symmetrically in both ears and progressively as a result of aging. Thus RM demonstrates the existence of cochlear conductive presbycusis and can be considered a useful test of stiffness of the cochlear partition.

Adolescent↗