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Biomedical subjects

C Araki

Publications and source records attributed to C Araki.

At least 19 recordsLinked to original sources
PubMed1993

[Report of three cases of purple urine bag syndrome which occurred with a combination of both E. coli and M. morganii].

Purple urine bag syndrome is a rare phenomenon in which bags turns purple or blue following catheterization. This phenomenon was reported to occur by Providencia stuartii in the presence of indicanuria. We reported herein three females above 75 years of age having a similar phenomenon. All were bedridden chronically and constipated. In these cases, no growth of P. stuartii was found on repeated urine culture, but Escherichia coli and Morganella morganii were concomitantly isolated during the blue bags. It is suggested that purple urine bag syndrome develops in a combination of E. coli and M. morganii besides P. stuartii.

Aged↗
PubMed1991

[A case report of diarrhea associated with Giardia lambria and Salmonella].

We report a case of diarrhea associated with Giardia lambria and Salmonella. A 28-year-old male who had no chance to go abroad visited our hospital with complaints of abdominal pain, watery diarrhea and fever, but his symptoms persisted in spite of medication. He was admitted to our hospital on the next day for definite diagnosis and treatment. Many trophozoites of Giardia lambria were recognized in the feces. The symptoms were improved using metronidazole, so he was discharged on the 8-th day. The cause of this double infection was not determined. The domestic infection like this case is rare in Japan.

Adult↗
PubMed1985

HLA polymorphisms in a Han Chinese population of Sichuan.

This study reports the phenotype frequencies (PF) and gene frequencies (GF) of a homogeneous Sichuan Han Chinese population by typing of unrelated 229 individuals and 16 families for HLA-A, B, C, DR and DQ antigens. The frequencies of Bw67, Bw71, DRw12, DRw13 and DRw14 are the first to be reported in Chinese. Two two-locus haplotypes with significant linkage disequilibrium among the Sichuan have also been listed.

Asian People↗
PubMed1983

Phagocytosis of cytoplasmic blebs derived from smooth muscle cells by fibroblast-like cells and macrophages in the post-partum rat uterus.

Numerous blebs were observed in contact with smooth muscle cells (SMC) by light microscopy in the myometrium of the rat uterus after parturition. Electron-microscopically the cell surface of SMC showed bulbous protrusions, which often lacked a basement membrane and were less electron-dense than the surrounding cytoplasm or sometimes nearly electron-lucent. Many bulbous protrusions were separated from SMC and became the isolated structures which we called cytoplasmic blebs. These bulbous protrusions and cytoplasmic blebs were often found to be phagocytosed by fibroblast-like cells and macrophages. A series of these tissue changes in the uterine myometrium after delivery, possibly due to hypoxic conditions, contribute to a rapid involution of SMC which have enlarged during pregnancy.

Animals↗
PubMed1983

Collagenase from the culture medium of rabbit colon wall with special reference to the latent type and substrate specificity.

Latent and active forms of collagenase were detected in culture media of the normal rabbit colon. During culture, the collagenase appeared to be produced by surviving and growing mucosas on the degenerated or necrotic colon wall. Type III collagen was most readily degraded by the collagenase, followed by type I and II collagens. The collagenase did not attack type IV or V collagens. The latent collagenase was activated by trypsin and chaotropic agents such as 3 M NaSCN or NaI, and autoactivated gradually during storage. Activated latent collagenase showed the properties of metalloproteinase as in the active collagenase. The apparent molecular weights, determined by calibrated Sephadex G-75, were 39,000 and 31,000 for the latent and active enzymes, respectively. After 12 h of tissue culture, the latent collagenase appeared in the culture media 10-20 h earlier than the active collagenase. The collagenase in the culture media of the early period was mainly the latent form, while the media of the late period contained a large amount of the active form.

Animals↗
PubMed1982

Polymorphism of properdin factor B in Japanese. Description of a rare variant and data of association with HLA and C2.

Polymorphism of the properdin factor B (BF) was investigated using an agarose gel immunofixation electrophoresis in 487 unrelated healthy adult Japanese who were already typed for HLA-A, -B, -C and C2. Besides the previously reported phenotypes in Japanese (S, FS, and F), a rare heterozygous phenotype (tentatively maned FTS) was observed once. The estimated allele frequencies for BS*S, BF*F, and FB*FT (F Tokyo) were 0.801, 0.198, and 0,001 respectively. The relative electrophoretic mobility of the variant band of type FTS was measured by Dr. G Mauff to be F 0.75. The conversion fragment Bb of the type showed a double-banded pattern. BF hemolytic activity of the FTS individual was at the same level as other phenotypes. Statistical tests for the phenotypic data of BF with HLA-A, -B, -C, and C2 indicated the presence of the following significant associations in Japanese: Aw33-BF*F, A11-BF*S, Aw24-BF*S, B15-BF*F, B17-BF*F, Bw44-BF*F, B7-BF*S, Bw52;-BF*S, BW54-BF*S, BW59-BF*S, Cw3-BF*F, C2*AT-BF*F, and C2*A'-BF*F.

Adult↗
PubMed1981

Genetic polymorphism of the complement C2 in Japanese.

Genetic polymorphism of the second component of human complement (C2) was investigated in 521 unrelated healthy adult Japanese using isoelectric focusing in polyacrylamide gel followed by a specific hemolytic overlay method. Besides the phenotypes reported previously (C, AC and BC), a relatively infrequent double-banded phenotype (tentatively named A'C) was observed. Moreover, a homozygous variant (A) and a heterozygous "double" variant (AB) were observed. The estimated frequencies for the common allele, C2c(= C2(1)), and the variant alleles, C2A, C2B(= C2(2)) and C2A' were 0.939, 0.034, 0.022, and 0.006, respectively. The results of further typing for HLA-A, -B, -C specificities indicated the presence of significant associations of C2A with HLA-B15 and with A26, and of C2B with HLA-Bw61. These findings support our previous observation that in Japanese there are allelic combinations showing linkage disequilibrium between C2 and HLA loci which are different from those in Caucasians, and that the C2 structural locus is more closely linked to HLA-B than to HLA-A. C2 hemolytic activities of each phenotypes were assayed. The mean activity of type AC sera was significantly higher than that of type C or type BC, while there were no differences in the activities among the types C, BC or A'C. Also presented are two pedigrees demonstrating the segregation of C2 with HLA alleles in which a homozygous C2 A or C2 B individual was observed.

Alleles↗