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C Ardeleanu

Publications and source records attributed to C Ardeleanu.

8 recordsLinked to original sources
PubMed1981

[Early repair of rupture of the posterior urethra in males. Report on 10 cases (author's transl)].

Repair operations were performed in 10 men with recent ruptures of the posterior urethra, between 1972 and 1980. One-stage segmental urethrectomy and end-to-end urethrorrhaphy was performed immediately (5 cases) or deferred to a late date (5 cases), with (2 cases) or without (8 cases) protective cystostomy. The origin of the lesions in these cases is discussed. The results obtained in these 10 patients are compared with those observed in 6 other cases treated urgently by cystostomy, with or without perineal drainage, followed by urethral reconstruction after a period of 2 to 6 months. Healing occurred within a mean period of 27 days in the first group, and 185 days in the second. Urinary fistulae developed in 20 p. cent of the patients in the first group, and 17 p. cent of those in the second group. Urinary continence was good in 100 p. cent of the first and 67 p. cent of the second group, a sterile urine being obtained in 100 p. cent and 83 p. cent of cases respectively. Sexual disorders were reported in 10 p. cent of the first and 67 p. cent of the second group. The authors conclude that urgent immediate or deferred reconstruction should be conducted in recent ruptures of the posterior urethra in men. Micturition urethrography after IVU. and retrograde urethrography, are essential investigations for detecting the lesions. Retrograde urethrography should be conducted with a small quantity (10 ml) of contrast medium, as soon as possible after plastic surgery. The authors employ segmental urethrectomy followed by end-to-end urethrorrhaphy, which has given better results than Solovov-Badenoch's urethroplasty.

Adult↗
PubMedDate not supplied

Sweat gland tumors with stromal haemangiomatous component: an undescribed type of skin tumors. Report of four cases.

An undescribed type of skin tumour, discovered in four cases, is reported. It is characterized by sweat-gland tumours (benign or malignant), with a common stromal haemangiomatous component which confers to it a peculiar pattern. Histogenetic possibilities are discussed. A collision mechanism between a pre-existent hamartomatous component (haemangioma) and a recent sweat-gland growth may be responsible for the appearance of this type and we think that this picture is more frequent but unidentified because, to our knowledge, it was not described up to the present paper.

Adult↗
PubMedDate not supplied

Histopathological study on inflammation in cholecystoses.

At present, according to the unanimously accepted data, cholecystoses are noninflammatory, nonlithiasic, gallbladder diseases. However the authors' experience has proved that the inflammatory process is much more frequent than it is believed and often associated also with lithiasis, a fact which, in the authors' opinion, would justify a reconsideration of this group of diseases. This study, based on histopathologic examination, was carried out in 1,630 gallbladder specimens, surgically removed. Out of these, 278 (17.05 per cent) were identified as cholecystoses; 156 out of them were cholesteroloses and 122 diverticular diseases of the gallbladder. Inflammation as a well defined morphologic process was found in 104 cases (66.67 per cent) of cholesterolosis and in 119 cases (97.54 per cent) of diverticular disease, therefore 80.21 per cent of the cases of cholecystosis examined were associated with inflammation. As regards lithiasis, it was present in 131 of the cases (46.76 per cent). The inflammatory process presented a chronic aspect with no other particular morphologic characteristics. By correlating the histopathologic data with the clinical evolutive ones, it was observed that the presence of inflammation corresponded with a clinical evolution of the disease of about three years. The authors believed that the group of cholecystoses should be reconsidered bearing in mind that inflammation is present in most of the cases and in almost half of them it is associated with lithiases. Under these conditions the sphere of chronic nonlithiasic, noninflammatory gallbladder diseases becomes considerably reduced today.

Cholecystitis↗
PubMedDate not supplied

Tumoral infiltrate after local treatment with interferon in squamous cell carcinoma.

Using monoclonal antibodies UCHL-1 (T lymphocytes), MT-1 (pan T) and L-26 (B lymphocytes) in the study of the tumoral infiltrate after local treatment with alpha interferon (Roferon) in patients with squamous cell carcinoma of the lower lip, it was observed that: the proportion of UCHL-1 positive cells was between 30% and 80%, the proportion of MT-1 positive cells was of 85% and that of the L-26 positive cells was of 30% of all the cells in the infiltrate. In the area in which after treatment with interferon the tumoral structures had disappeared, the proportion of T lymphocytes was smaller than in the areas in which the tumoral structures were still present. The therapeutic effect of interferon is due both to the direct effects on the tumoral cell and also to the indirect effects, namely the activation of the cytotoxic T lymphocytes and of other cells in the tumoral infiltrate.

Adult↗