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Biomedical subjects

C Auerbach

Publications and source records attributed to C Auerbach.

14 recordsLinked to original sources
PubMed1992

Differential expression of cytochrome P-450 in proliferating and quiescent cultures of murine lung epithelial cells.

Expression of the cytochrome P-450 monooxygenase activity 7-ethoxyresorufin O-deethylase (7-ERD) was surveyed in proliferating and quiescent cultures of murine cell line C-10, a non-tumorigenic line of presumed alveolar type II origin. 7-ERD activities were undetectable in subconfluent/proliferating cultures but became detectable once the cultures had become confluent and their growth had arrested due to contact inhibition. Serum deprivation of subconfluent cultures resulted in a rapid inhibition of cell proliferation and the subsequent expression of 7-ERD. These results suggest that 7-ERD expression is regulated as a function of the proliferative status of C-10 cells.

Animals↗
PubMed1992

Helping patients in the supportive milieu of a community residence program for the chronically mentally ill: conceptual model and initial evaluation.

The Community Residence Program described is sponsored by an urban teaching hospital and supported by state funds. The program uses scatter-site apartments in the community to house 120 patients in a therapeutic milieu as part of their comprehensive aftercare treatment. The program stresses teaching the skills of daily living to patients with chronic, psychiatric illnesses. The conceptual model used is based on challenges and tasks appropriate for this population. Preliminary evaluation findings suggest that the program is successful in teaching patients social skills, helping them adhere to medical regimens, perform household chores and observe fire safety regulations.

Activities of Daily Living↗
PubMed1989

Level of object representation and psychic structure deficit in obese persons.

The structural deficit and external regulation hypotheses of addiction state that addicts do not have adequate psychic structure with which to regulate painful affects internally. They instead use their drug of choice as an external regulator to self-medicate painful affects. This study tests whether the hypotheses can be applied to obese persons, for whom food may be the drug of choice. The level of object representation of 22 moderately obese and 24 normal weight subjects was compared using the Blatt Family Interaction Questionnaire. The mean level of object representation of both parents was lower for the obese subjects than for the normal-weight subjects. This finding supports the structural deficit and external regulation hypotheses of food addiction.

Adaptation, Psychological↗
PubMed1978

Diepoxybutane-induced male-transmissible X-autosome translocations in Drosophila melanogaster: a test of the supporting evidence for the Lifschytz-Lindsley model of spermatogenesis.

The Lifschytz-Lindley model of spermatogenesis in heterogametic animals postulates a stage of gene inactivation during spermatogenesis, which affects the X-chromosome and the autosomes at different times. The frequent male infertility of X-ray induced X-autosome translocations is attributed to disruption in the timing of this stage by breaks that occur in the interior euchromatic portion of the X. Indeed, all male-fertile X-ray induced translocations between the X and an autosome had their breakpoints in the proximal or distal portion of the X. We now show that this was true also for 16 male-fertile X-autosome translocations that had been induced by an alkylating agent, diepoxybutane (DEB). The significantly higher proportion of male-fertile X-translocations in this experiment than in experiments with ionizing radiation apparently is due to a preference of diepoxybutane for the induction of breaks in the "permissive" regions of the X. Older data suggest that this preference is even stronger for mustard gas as chromosome-breaking agent. While these data do not add further evidence to the Lifschytz-Lindley model, they remove a potential objection to it.

Animals↗
PubMed1975

"Shaping" of frequency discrimination performance using only intrinsic reinforcement.

This experiment compared two modes of practice at a difficult frequency discrimination, i.e., one in which the frequency difference was initially correctly discriminated only 65% of the trials in a two-alternative forced-choice task. One group of Ss (N = 13) was assigned to a progressive-practice group, in which the frequency difference to be discriminated was progressivley changed from a large, easy, difference to the difficult, small, difference. The other group of Ss (N = 13) received the same amount of practice as the first, but all at the difficult discrimination. Only the progressive-practice group improved their discrimination performance. Since no feedback was given, the effect of progressive practice is interpreted as "shaping" Ss' attentional response by virtue of the information provided by the successively more difficult discriminations. This "shaping" process is potentially available as a learning mechanism for other fine discriminations.

Attention↗
PubMed1975

Eye movement in perception of another person's looking behavior.

Eye contact is a non-verbal behavior category of major concern in the study of social interaction. Within this category many behaviors are included which serve a wide range of functions. It was hypothesied that (1) one of the important stimulus properties that distinguish these behaviors is the movement pattern of the eye and (2) that people use different criteria to judge whether another person is looking at them, depending upon whether the other person is displaying a dynamic or static eye presentation. Data are presented to support these hypotheses.

Eye Movements↗