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Biomedical subjects

C Auerhahn

Publications and source records attributed to C Auerhahn.

6 recordsLinked to original sources

Recognition and management of alcohol-related nutritional deficiencies.

Alcoholic beverages comprise an appreciable percentage of the total caloric intake of individuals in Western societies. Alcohol contains no usable nutrients and, in the chronic drinker, often replaces food. Chronic alcoholics frequently have evidence of nutritional deficiencies due to decreased intake, reduced uptake and impaired utilization of nutrients. Syndromes of nutritional deficiency seen in the alcoholic include anemias, neurological disorders, and vitamin and mineral deficiencies. Alcoholics represent the largest group of patients with treatable nutritional disorders in Western countries. Recognition and management of alcohol-related nutritional deficiencies may assist in the identification of high-risk individuals and may result in improved health status with reduced morbidity and mortality.

Alcoholism↗

Continuous subcutaneous insulin infusion (CSII) reduces counter-regulatory hormone concentrations in a patient receiving enteral hyperalimentation.

A 61-year-old male, while recovering from a Whipple's procedure for pancreatic carcinoma, was treated for 13 days with an insulin infusion pump for diabetes exacerbated by enteral hyperalimentation. Treatment with continuous subcutaneous insulin infusion resulted in improved blood glucose control. Associated with this improvement was a reduction in plasma cholesterol, triglyceride and free fatty acid levels. Plasma epinephrine, norepinephrine, glucagon and cortisol concentrations were also lowered although growth hormone levels remained unchanged. It is concluded that enhanced metabolic control during hyperalimentation results in a decrease in counter-regulatory hormone levels and an improvement in the catabolic state in this patient. These preliminary observations provide evidence for maintaining euglycemia in diabetic patients while receiving nutritional support.

Blood Glucose↗

Exercise and diabetes.

Exercise has variable effects on diabetes control. It may cause deterioration in diabetes regulation if patients are hyperglycemic, whereas it may reduce blood glucose levels in well-controlled patients. Factors influencing the magnitude of blood glucose reduction include timing of meal ingestion, peak of insulin activity and whether the extremity injected is exercised. Plasma cholesterol and triglyceride levels decrease while high-density lipoprotein levels may increase with activity.

Blood Glucose↗

Insulin pump therapy improves blood glucose control during hyperalimentation.

The present study investigated the feasibility of basal continuous subcutaneous insulin infusion (CSII) in four patients with postoperative sepsis or extensive burns during continuous enteral hyperalimentation with 2,500 to 3,000 calories/day, containing approximately 390 g of simple carbohydrates. The mean duration of CSII treatment was 16.8 days (range, seven to 32 days). The mean capillary blood glucose level fell from 322 +/- 52 mg/dL during pre-CSII therapy to 195 +/- 33 mg/dL during CSII therapy. Only 1.3% of 1,254 capillary blood glucose values were less than 60 mg/dL. Most values (61.6%) were between 61 and 200 mg/dL. The mean insulin infusion rate was 2.5 +/- 1.5 units/hr. These preliminary observations suggest that basal infusion CSII is a safe and effective means of improving blood glucose control in patients receiving enteral hyperalimentation despite the high glucose intake and presence of insulin resistance. Thus, CSII therapy can enhance the metabolic response to hyperalimentation without requiring an intravenous access route.

Blood Glucose↗

Assuring quality and access in advanced practice nursing: a challenge to nurse educators.

In an environment characterized by a projected over-supply of primary care providers and a public seeking higher quality, cost-effective care, advanced practice nurses will be measured not only by their comparative value in delivering conventional primary care, but also by the uniqueness of their contributions to health outcomes. These value-added skills, distinctive to nursing practice at all levels, include health education, disease prevention, health promotion, community resource access, and partnerships with patients. Government, private payors, and national and state regulators all authorize increasingly independent practice by advanced practice nurses. When advanced practice nurses assume such fully accountable primary care roles, their title and certification should be distinctive to that level of practice. A Doctor of Nursing Practice (DNP) degree would signal to the public that nurses--at their highest practice competency--are at the same level as other health professionals holding doctorates (such as MD, DDS, or PharmD).

Clinical Competence↗