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Biomedical subjects

C Aydin

Publications and source records attributed to C Aydin.

26 records · Page 2Linked to original sources
PubMed1992

Oligohydramnios induced by maternal indomethacin therapy.

Indomethacin is a potent tocolytic agent used in premature labor. The most observed adverse effect was the constriction of ductus arteriosus, causing persistent fetal circulation postnatally. Until recently, decrease in amniotic fluid during treatment with indomethacin has been shown partly by subjective methods. In comparison with posttreatment results, using "amniotic fluid index", transient decrease in amniotic fluid was determined semi-quantitatively.

Female↗
PubMedDate not supplied

Stone disease in kidney transplantation.

The aim of this study was to evaluate etiologic, diagnostic, and management aspects of stone disease in renal transplant recipients and donors. Calculi from five patients were analyzed. The immunosuppressive regimen included tacrolimus or cyclosporine, mycophenolate mofetil, and corticosteroids in all cases. The etiology of the stone disease was cadaveric donor-gifted in one patient and de novo stone formation after transplantation in two patients. Additionally, stone disease was found and treated in living related donors in two patients. The mean follow-up was 32.4 +/- 19.7 months. In the living related donors, stones were initially treated by ESWL. Pyelotomy at the back table during the transplantation was required in one of them. The patient with cadaver-gifted stone was also treated by ESWL. In patients with de novo stone formation after transplantation, the stones were related to urinary infections and foreign body double-j (JJ) stent. A small stone in one of these patients (de novo formation) passed spontaneously after removal of the foreign body. Endoscopical lithotripsy was performed in the other patient. Stones are more frequently transplanted with allografts than expected; therefore, preoperative imaging of the donor is important. ESWL is recommended for medium-sized calculi in transplant kidneys. JJ stent insertion before ESWL might be needed in stones larger than 10 mm.

Adult↗
PubMedDate not supplied

Accuracy of frozen section diagnosis in ovarian tumors: Is there a change in the course of time?

A retrospective study of 222 ovarian biopsy results between January 1, 2000 and August 31, 2002 was examined to determine the accuracy of frozen section diagnosis. In addition we reviewed all previous studies that examined the accuracy rates of frozen section diagnosis in ovarian tumors. Histopathologic examination results of frozen section biopsies were concordant with paraffin diagnosis in 92% of all cases. The sensitivity rates for benign, malignant, and borderline ovarian tumors were 98%, 88.7%, and 61%, respectively. There were five (2.2%) false-positive (overdiagnosed), and 13 (5.4%) false-negative (underdiagnosed) patients in frozen section examination. Frozen section examination of mucinous tumors showed higher underdiagnosis rates (20%). Review of previous studies showed no significant variation in accuracy rates of frozen section diagnosis for benign and malignant ovarian tumors, in relation with time. We found low accuracy rates for borderline ovarian tumors which was similar with the previous studies. However, there were consistent and relatively higher sensitivity rates for borderline ovarian tumors in the recent studies. As a result, we conclude that frozen section evaluation in identifying a malignant or benign ovarian tumor is accurate enough for the correct diagnosis. Since accuracy rates for borderline ovarian tumors are low, we should have more improvement in the correct diagnosis.

Adenocarcinoma, Clear Cell↗
PubMedDate not supplied

Comparison of granisetron with granisetron plus droperidol combination prophylaxis in post-operative nausea and vomiting after laparoscopic cholecystectomy.

The aim of this study was to evaluate the effects of granisetron and granisetron plus droperidol combination therapy on post-operative nausea and vomiting (PONV) in 60 patients who had undergone elective laparoscopic cholecystectomy. Induction of anaesthesia was achieved using 5 mg/kg thiopentone, 2 micrograms/kg fentanyl and 0.5 mg/kg atracurium, and anaesthesia was maintained with 2-2.5% sevoflurane. The patients were randomly assigned to two groups: group G (granisetron) (n = 30) patients received 3 mg granisetron and group GD (granisetron plus droperidol) (n = 30) patients received 3 mg granisetron and 1.25 mg droperidol shortly before the induction of anaesthesia. PONV incidence was recorded post-operatively at 15 min, 30 min, 60 min, 2 h, 4 h, 12 h and 24 h. While PONV prophylaxis provided almost complete emetic control in patients who received the granisetron plus droperidol combination, patients who received granisetron prophylaxis alone experienced PONV more frequently at 30 min and 60 min post-operatively. We conclude that addition of a low dose of droperidol to granisetron prophylaxis is more effective than granisetron prophylaxis alone for successful control of PONV.

Adult↗