Ichthyosis has been classified on a genetic basis. Four varieties--ichthyosiform erythroderma, lamellar ichthyosis, Refsum's syndrome and the Sjögren-Larsson syndrome--are inherited as autosomal recessive traits. One type is inherited as a sex-linked recessive trait while another variety of ichthyosis (with or without atopy), bullous ichthyosiform erythroderma, and very rarely ichthyosis hystrix are due to autosomal dominant genes.

Humans↗

PubMed1965

Inheritance of factor 8.

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Blood Group Antigens↗

PubMedDate not supplied

On the distribution of frequencies of mutation to genes determining harmful traits in man.

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Genetic Diseases, Inborn↗

PubMedDate not supplied

Neural tube defects in New South Wales: management and preventive policies, 1965-1980.

This paper reviews the results of the programme of antenatal testing and selective termination of fetuses with anencephaly and spina bifida in New South Wales over the last eight years. It discusses the problems associated with pregnancy screening, with reference to those involved in selection for treatment of newborn infants with spina bifida. The incidence of neural tube defects has been declining, and this, although possibly the result of early termination of affected fetuses, may have its basis in a worldwide trend. Preventive action based on a more precise understanding of aetiological factors will further decrease the incidence, thereby reducing the load of long-term handicapped survivors.

Abortion, Legal↗