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Biomedical subjects

C B Liden

Publications and source records attributed to C B Liden.

7 recordsLinked to original sources

Intellectual, neuropsychological, and achievement outcomes in children six to eight years after recovery from Haemophilus influenzae meningitis.

Twenty-four grade school children who had sustained an earlier episode of Haemophilus influenzae type b meningitis were tested, along with a group of 24 school-aged siblings. Evaluations consisted of tests of IQ, academic achievement, and neuropsychological skills. Parents completed forms rating each child's behavioral adjustment and temperament. Available school-administered standardized achievement tests were also obtained. Information relating to the episode of meningitis was extracted from the medical charts of each child who had had meningitis in order to investigate the relationship of these parameters to developmental outcome. Results showed that, compared with nearest-age siblings, children who had had meningitis scored lower on performance IQ and full-scale IQ. The group that had had meningitis also performed more poorly on several neuropsychological tasks. However, the groups did not differ in verbal IQ, and they performed comparably on all academic measures. Significant behavioral adjustment problems were absent from both groups, and there were no notable differences in temperament. Although findings support the existence of postmeningitis sequelae, the selective nature of the deficiencies observed indicate that prognosis for children in the age range examined may be better than that suggested by earlier studies.

Child↗

TRANSACT--a model for integrating clinical practice and longitudinal research.

To effectively deal with the high-risk infant and his outcome, it would appear that clinicians and researchers must, in a sense, place themselves "at-risk." They must recognize the limitations of a reductionistic, biomedical model when applied to this population and its problems. They must move beyond this traditional model to a so-called "biopsychosocial model" which acknowledges the uncertainties of human development and its transactional character. To do so, they must also seek to break down many traditional "boundaries" that have served to inhibit a better understanding of the high-risk infant. These boundaries include those between disciplines, between clinicians and researchers, between assessment and treatment, between cost efficiency and comprehensiveness, and those between quantitative and qualitative methodologies to name a few. This process must not be one of all or none exclusion, where a uniform perspective is adopted in isolation and applied to all aspects of the problem. Rather it must be a combination and synthesis of many perspectives. In essence, the construct used to understand and study the high-risk infant and his outcome should be consistent with the transactional and multifactorial nature of the problem. These tasks are formidable and threatening to undertake, particularly when they do not always yield the type of outcomes we have been conditioned to expect: "hard" data; narrow etiologies; and successful cures. However, failure to take such "risks" would seem to impede a further understanding of the at-risk infant. The T.R.A.N.S.A.C.T. model presented here is offered as a working construct which has yet to be fully operationalized. Its perceived limitations will reflect the background, biases and perspectives of the reader. Hopefully, it will serve to stimulate those interested and involved in the high-risk infant and his outcome to modify, refine or build upon their current approaches.

Child↗

Audiologic aspects of learning and behavior.

To effectively deal with learning and behavioral problems, physicians must acquire a new knowledge base and interact meaningfully with professionals from a variety of disciplines. They must be aware that audiologic factors are only one part of a complex matrix of components contributing to learning and behavior. Although the exact nature of these components is still being defined, their interrelationship can be hypothesized. An individual can overcome the uncertainties and avoid inappropriate diagnoses in this field by applying a comprehensive, descriptive diagnostic process. With a broad understanding of the transactional model of learning and behavior, physicians can ensure that audiologic problems are defined and addressed appropriately. By acknowledging this approach in the identification, assessment and management of children with learning and behavioral dysfunction, the physician can become a powerful advocate for these children.

Child↗

Phencyclidine. Nine cases of poisoning.

In nine cases of phencyclidine hydrochloride poisoning, early signs of overdose included drowsiness, nystagmus, miotic pupils, blood pressure elevation, increased deep tendon reflexes, ataxia, anxiety, and agitation. In more severe cases, seizures, spasticity, and opisthotonos were seen in addition to deep coma and respiratory depression. Treatment included removal by emetics or lavage, hydration, and a quiet, reassuring environment. Spasticity, agitation, and ocular manifestions responded to diazepam. Psychiatric intervention was instituted after the patients were stable and no longer agitated.

Adolescent↗