A case of primary Sjögren's syndrome, complicated by cryoglobulinaemic glomerulonephritis, pericardial and pleural effusions.
Primary Sjögren's syndrome (SS1) complicated by glomerulonephritis is rare and is usually associated with the presence of cryoglobulins. Cryoglobulinaemic glomerulonephritis as described in type II essential mixed cryoglobulinaemia, characterized by the presence of deposits of cryoglobgulins within the glomerular capillary lumen, occurring in SS1 has previously been reported only once in the literature. Our case was also complicated by pleural and pericardial effusions. We discuss the treatment options available for the renal lesion.
Cryoglobulinemia↗