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Biomedical subjects

C Bölter

Publications and source records attributed to C Bölter.

13 recordsLinked to original sources
PubMed1991

[Effects of diltiazem in acute and long-term administration].

In 16 patients with unstable angina pectoris haemodynamic and clinical effects of diltiazem were investigated. In a second group patients (n = 11) with unstable or therapy-refractory course the long-term effect was tested. The acute intervention with injected and infused diltiazem via an improved oxygen balance due to decreased minute work and reduced product of cardiac frequency and pressure stabilized the clinical picture from the haemodynamic aspect. The decreases of the ST segment were significantly lower. In the long-term use a significant influence on the frequency of angina pectoris with increase of the range of efficacy by one NYHA-state was the result. Diltiazem can be regarded as alternative medicament in unstable phases and in therapy-refractory courses of the chronic coronary heart disease.

Angina, Unstable↗
PubMed1990

[Echocardiography during pregnancy--longitudinal studies in primigravidae].

As a result of hormonal changes processes of adaptation of the cardio-vascular system occur during pregnancy. These regulative changes are the basis for the present echo-cardiographic study which was made under standardized conditions with healthy primigravidae (n = 20) compared to nulligravidae (n = 24). Besides blood pressure and heart frequency dimension and volume sizes of the left ventricle (LV) as well as the LV-weight of muscle and the peripheral vascular resistance were analysed. As result significant increases from the 15th to the 35th week of pregnancy (SSW) could be found for the following parameters: heart frequency, arterial blood pressure, endosystolic volume of the left ventricle, cardiac output, left ventricular weight of muscle (p less than 0.01) endosystolic diameter of the left ventricle, enddiastolic volume of the left ventricle and heart index (p less than 0.05). The peripheral resistance was continuously decreased in the course of pregnancy (p less than 0.01). Compared to non-pregnant women the following parameters showed significantly higher values: heart frequency, cardiac output and heart index (p less than 0.01). The peripheral resistance was significantly lower in pregnant women compared to non-pregnant women (p less than 0.01). From the results the conclusion can be drawn that with statistic certainty echocardiography records adaptive processes of the circulation regulation relative to pregnancy and enables a separation in the groups of pregnant and non-pregnant women.

Cardiac Output↗
PubMed1988

[The status of prazosin in therapy of chronic heart failure].

Cardiac dysfunction and neurohumoral dysregulation show that the administration of vasodilators is reasonable in a cardiac insufficiency which is therapy-refractory against glycosides and saluretics. The alpha 1-blocker prazosin is a potent substance. On the basis of haemodynamic investigations of 55 patients the acute effects are demonstrated. Depending upon the degree of the cardiac insufficiency and the sympathetic dysregulation--measured at the behaviour of the resistance--the acute effects are convincing in more than 60% of the patients. For the long-term course patients with unequivocal initial improvement are suitable. This group can undergo a satisfactory therapy for a longer time by means of a carefully increased dosage, by corrections of the application of saluretics and by short interruptions of therapy and by the change of the dilator, respectively, or by an additional administration of another vasodilator. In the total spectre of the vasodilators which are administered in cardiac insufficiency prazosin occupies one of the first places.

Cardiomyopathy, Dilated↗
PubMed1980

[Douglas' pouch swab for detection of anaerobic asporous micro-organisms (author's transl)].

Bacteriological diagnosis was applied to Douglas' pouch swabs taken off 119 patients, most of them with non-inflammatory genital diseases. Purely anaerobic cultures were recorded from 11.8 per cent, mixed anaerobic-aerobic cultures from 8.4 per cent, and purely aerobic cultures from 56.3 per cent. Cultures remained sterile in 23.5 per cent of all cases. Forty-six of those patients were afflicted with uterine myomatosis, a group from which the following results were obtained: purely anaerobic cultures in 21.7 per cent of all cases, mixed anaerobic-aerobic cultures in 6,5 per cent, purely aerobic cultures in 54.4 per cent, and sterile cultures in 17.4 per cent. The importance of such sited flora to both genesis and kinetics of pelvic inflammations is discussed.

Anaerobiosis↗