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Biomedical subjects

C Balachandran

Publications and source records attributed to C Balachandran.

At least 19 recordsLinked to original sources
PubMed1991

Rhinosporidium seeberi: light, phase contrast, fluorescent and scanning electron microscopic study.

Phase contrast microscopic study indicated the multilayered structure of the sporangial wall of R. seeberi while the scanning electronmicroscopic study revealed a trilaminated wall compared to a thick double walled light microscopic structure. The scanning electronmicroscopy revealed the spores of varying sizes which were found either discretely or in groups interconnected and seen attached to the inner aspect of the sporangial wall. Autofluorescence of sporangia and spores was observed under microscope. Acridine orange staining revealed the presence of DNA materials in the spore and sporangia.

Acridine Orange↗
PubMed1990

Ocular rhinosporidiosis in Tamil Nadu, India.

A high incidence of ocular rhinosporidiosis in Kanyakumari district of Tamil Nadu, India is reported. Among the four taluks (sub-division for administration), highest occurrence was found in Agastheeswaram taluk (51.2%) followed by Kalkulam (24.4%), Thovalai (22%) and Vilavancode (2.4%). The disease occurred among both sexes equally and preponderance of a particular sex was not observed. The young adolescents were found to be more susceptible. The disease was found in all socio-economic strata and among all communities and persons belonging to different religious groups. Most of the patients gave a history of bathing in muddy stagnant pools of water.

Adolescent↗
PubMed1990

Incidence and clinicopathological studies on rhinosporidiosis in Tamil Nadu.

A clinicopathological study on 83 cases of rhinosporidiosis attended at Tirunelveli Medical College Hospital during 1979 to 1984 from Tirunelveli, Tamil Nadu revealed its endemicity. The season has no apparent influence on the incidence probably due to chronicity of the disease. The incidence was mostly seen in 11-30 years age group (57/83). Males were predominantly affected (60/83). Temperature, pulse, respiration, blood pressure, bleeding and clotting times were within the normal range. Urinalysis revealed no abnormal constituents. Haematological examination revealed that the haemoglobin level was below normal ranges (males-8.58 g/dl; females-7.71 g/dl). Though the total leucocyte counts were found to be normal the differential count showed a slight monocytosis (males-8.39%, females-9.17%).

Adolescent↗
PubMed1988

Epidemiological survey of rhinosporidiosis in Kanyakumari district of Tamil Nadu.

One hundred and twelve nasal polyps received along with full history from three different hospitals of Kanyakumari district of Tamil Nadu during the period 1983-1987 were found positive for rhinosporidiosis on histopathological examination. Among the four taluks (countries) the majority of the cases (41.1 per cent) came from Agastheeswaram, followed by Kalkulam (28.6 per cent), Thovalai (17.0 per cent) and Vilavancode (13.3 per cent). The 11-20 years age group found to be highly susceptible (60 per cent). There was no sex prepondence in contracting the disease as the cases were evenly distributed between both sexes. These findings exhibited the endemic nature of the disease in Kanyakumari district. Unreported cases to an extent of 9 to 40 per cent were encountered during the ENT disease diagnostic camps conducted in nine high incidence villages. Further 8 more cases were detected in addition to cases attended in the hospitals and ENT camps when a complete enumeration of cases was undertaken in Pallam village. Thus the actual number of cases found in the district need a stratified random sampling.

Adolescent↗
PubMed1988

Influence of dietary aflatoxin on certain serum enzyme levels in broiler chickens.

Experimental aflatoxicosis was produced in 'Cobb' broiler chickens by feeding them with dietary aflatoxin at concentrations of 1 and 3 ppm for a period of four weeks from 0 to 28 days. Twelve birds in triplicate were used for each treatment of which three from each replicate were sacrificed at weekly intervals for enzymatic estimations of SGPT, SGOT, Serum amylase and serum lipase. Thus each treatment contained nine weekly observations and 36 observations in total. The SGPT activity was not found in appreciable amounts either in control or in toxin treated birds. However, the SGOT levels were in measurable amounts and elevated levels were observed in toxin treated birds from first week onwards at both levels of toxin and was dose related. The treatment means of SGOT differed significantly (P less than 0.05). The serum lipase levels increased from first week onwards and the treatment means showed significant difference (P less than 0.01). Serum lipase changes in toxin treated birds occurred to about the same extent. But the serum amylase levels decreased from first week onwards and their treatment means differed significantly (P less than 0.01) at both levels of toxin treated birds. Serum amylase concentrations decreased as the aflatoxin level increased in the diet.

Aflatoxins↗
PubMed1987

Rhinosporidiosis in bovines of Kanyakumari district, Tamil Nadu, India.

A survey on rhinosporidiosis in animals was conducted in Kanyakumari (K.K.) district of Tamil Nadu, India. Among 103 animals (40 bullocks, 45 cows, 15 heifers, 2 bulls and a buffalo), 19 (9 bullocks, 8 cows, 1 heifer and a she-buffalo) were found to be infected with Rhinosporidium seeberi. The study revealed the endemic nature of the disease in bovines of K.K. district. Agastheeswaram taluk contributed 52.6 per cent of positive cases followed by Kalkulam (26.2 per cent). The disease was also found in exotic cattle (1 Holstein Friesien (HF) cow, 1 Swiss Brown cow and 1 HF heifer). The rest 16 were indigenous non-descript cattle. There was no sex variance as the cases were evenly distributed between both sexes. One of the infected animals was a she-buffalo. A case of recurrence of growth was observed in a bullock. Another bullock had concurrent infection of both rhinosporidiosis and nasal schistosomiasis. All the animals were adults and aged except the heifer. All were nose-roped. Cows were stall fed but bathed in ponds.

Animals↗