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C Bartz

Publications and source records attributed to C Bartz.

26 records · Page 2Linked to original sources

Partial characterization of a renotropic factor.

In 70 experiments, the existence of a circulating renal growth factor was confirmed by 9.3% stimulation of 3H-thymidine into the DNA of renal fragments incubating for 90 min in the presence of sera from 20-hour unilaterally nephrectomized rats compared to sera from 20-hour sham-operated rats (p less than 0.001). Dialysis (7.4%, p less than 0.01) or removal of albumin (11.8%, p less than 0.001) from sera of both sham-operated and unilaterally nephrectomized rats did not appreciably change the magnitude of the statistically significant stimulation. When albumin-free sera were placed in boiling water for 1-3 min to coagulate protein, the stimulation was still significantly different from control (5%, p less than 0.05). Addition of sera from unilaterally nephrectomized rats (20 h) to isolated nuclei, even isolated nuclei removed from growing kidneys (72 h after unilateral nephroctomy), failed to enhance DNA synthesis significantly.

Animals↗

It all starts with an idea.

Great ideas make great research and provide the researcher with the shapes for growing the idea in an organized fashion. Successful research ideas are interesting, important, researchable, and doable. This article describes one way of organizing great ideas into successful research by using the research process, beginning with conceptualization/design and literature review, and proceeding through the articulation of the framework, purpose, assumptions, limitations, definitions, and hypotheses/research questions. Following the logical progression of the conceptualization of the idea will help the researcher to complete the grant application and be ready to develop and execute the methodology of the study.

Creativity↗

Comparison of the efficacy of AZT and PMEA treatment against acute SIVmne infection in macaques.

The antiretroviral drugs azidothymidine (AZT) and 9-(-2-phosphonyl-methoxyethyl)adenine (PMEA) were individually tested for prevention of simian immunodeficiency virus (SIVmne) infection in macaques (Macaca fascicularis). Macaques were pretreated with either drug before inoculation with SIVmne, and drug treatment was continued for four weeks. The virus, antibody, and clinical status of the macaques was monitored for up to 36 weeks following inoculation. While AZT prophylaxis resulted in reduced virus load in some macaques, PMEA prophylaxis was highly efficacious in preventing acute SIVmne infection.

Adenine↗

Nurses' views on preceptorship programs and preceptor and preceptee experiences.

As part of developing an Army Nurse Corps Preceptorship Program, a survey queried 70 Army Nurse Corps officers about preceptorship program content and process. Respondents provided information about personal, interpersonal, clinical, and environmental characteristics of preceptorships. The most important preceptor characteristic was clinical competence. Recommended program length was at least 6 weeks. Transition to clinical practice was a key objective of preceptees.

Adult↗