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Biomedical subjects

C Beck

Publications and source records attributed to C Beck.

At least 163 records · Page 9Linked to original sources

[How important is preservation of the accessory nerve in neck dissection?].

Preservation of the spinal accessory nerve in radical or modified neck dissection is oncologically accepted in order to avoid the sequelae of the so called "shoulder syndrome". In 23 patients, on whom 29 neck dissections had been performed, the functional results were evaluated on an average 2.6 years postoperatively. 19 patients were radiated post surgery. Clinical and electromyographic examination revealed paresis of 62% of the preserved accessory nerves. Nevertheless, only 48% of the patients suffered from the shoulder syndrome, the remaining were able to innervate or compensate for the resulting deficit. Postoperative functional exercises are mandatory to prevent the shoulder syndrome and to make the preservation technique a worthwhile concept.

Accessory Nerve↗

[Differential diagnosis of benign paroxysmal positional vertigo in Menière's disease].

135 patients with BPPV and 56 patients with Meniere's disease were evaluated critically. The reliability of the diagnostic criteria (history and physical examination, audiograms and vestibular function tests) were compared. History, physical examination and patients' complaints were inconclusive. Moderate or severe medio- or pancochlear inner ear damage was more reliable, but not pathognomonic of Meniere's disease. Patients with BPPV had normal hearing or a high-frequency loss. Electronystagmographically recorded vestibular function tests were unreliable in establishing the diagnosis. The most valid test to distinguish BPPV and Meniere's disease was Hallpike's positional test, using Frenzel's spectacles for better observation of the provoked nystagmus.

Adult↗

[Recurrent benign tumors of the parotid gland and their tendency for becoming malignant].

In 257 parotid adenomas lumpectomy led to tumour recurrence in 49.2%, superficial parotidectomy in 5.7% and total parotidectomy in 5.3%. 40 patients with recurrent tumours experienced eventually eight true malignant neoplasms. There were five carcinomas ex pleomorphic adenomas, one true malignant mixed tumour, and two undifferentiated carcinomas. Malignant transformation usually occurred with the 4th recurrence after 15.8 years. To prevent recurrence and secondary malignancy in parotid adenomas the lumpectomy technique should be omitted.

Adenoma↗

[How is a ranula formed?].

The origin of a ranula is due to obliteration of a minor duct of the sublingual gland. The main excretory duct remains patent.

Connective Tissue↗

A simple radio-isotopic method for the detection of bronchial inhalation during intensive care.

The high incidence of pneumopathy in intensive care units might be due to the pulmonary aspiration of gastric juice following gastro-oesophageal reflux. The paper describes a radio-isotopic method using material easy to install at the patient's bedside. This technique demonstrated aspiration of gastric juice in the lungs of 8 of 25 intensive care patients investigated. Such a method might be useful later to demonstrate that silent bronchial aspirations of gastric juice are responsible for pulmonary complications.

Humans↗

[Pathology of labyrinthine hearing loss].

The most common causes auf sensorineural deafness lie in the cochlea. Other causes are less numerous, such that our presentation will be limited to cochleal disturbances. In a general introduction we shall attempt to analyse the structural reactions, metabolism and circulation of the cochlea and the behaviour of the inner ear lymph to a noxa. The monotony of the reactions will be described as well as the reversibility of some of the changes which are observed. All these reactions play a part in the normal functioning of the inner ear. The special part of the presentation will discuss the different forms of sensorineural deafness with which we are confronted daily, taking particular account of morphological and metabolic characteristics. We shall attempt to summarise wellknown material, and discuss newer information in greater detail. We shall pont out possible causes of sensorineural deafness which have seldomly been discussed.

Adult↗

[Functional results of stapes surgery].

In 135 patients the functional results of stapedotomy and stapedectomy were controlled. As a rule, stapedotomy results were superior to stapedectomy results. Small hole stapedotomy using a 0.4 mm. teflon-wire piston yielded optimal sound transmission between 500-8000 Hz. In addition, this was the only technique to prevent cochlear damage at 4000 Hz and 8000 Hz.

Adult↗

[Otalgia].

Based on the sensibel innervation of the external and middle ear, the causes and therapy of otalgia are discussed. As a result, the classical definition of otalgia: "pain in the auricular area without concomitant ear pathology" should be maintained.

Cranial Nerve Diseases↗

[Obliteration of the mastoid cavity with porous tricalcium phosphate ceramic. Results 12 and 18 months after ceramic implantation in the hypotympanon of the pig].

The paper reports on the obliteration of mastoid cavities with resorbable tricalcium phosphate ceramic. As a model, we chose the pneumatic air cell system of the pig's hypotympanon, which resembles the human mastoid. At the time of surgery, the specimens were 10-12 weeks old. In a first group the cells of the hypotympanon were totally removed and the operation cavity was obliterated with adjacent layers of porous tricalcium phosphate ceramic. In a second group of specimens the air cell system was partly removed, leaving the apical part of the hypotympanon intact; the operation cavity was obliterated again with porous tricalcium phosphate ceramic. After 12 and 18 months survival the hypotympanons were removed and prepared for histological investigations. Those ceramic plates, lying close to the bony shell were strongly resolved and replaced by new bone. Other ceramic plates, however, especially those in the center of the implant, showed few signs of resorption and bony remodelling. Inside the ceramic implant there was hardly connective tissue. The space between the still unsolved ceramic plates was filled up with new bony tissue. This bone was partly structured and adjoined directly to the ceramic. The ceramic was integrated into the new bony tissue without any sign of an inflammation.

Animals↗

[Resorbable, porous tricalcium phosphate ceramic in middle ear surgery. Initial clinical results].

In our experimental study in the pig we could demonstrate that resorbable, porous tricalcium phosphate ceramic material is suitable for an obliteration of mastoid cavities (respectively the hypotympanon of the pig) or for the reconstruction of bony wall. To examine this material in a clinical study for middle-ear surgery, we chose 2 mm thick ceramic plates and segments of truncated cones. With the aid of a diamond drill and irrigation this ceramic can be treated easily. In 25 middle ears, the following reconstructive surgeries were performed with these ceramic implants: in 22 cases a partial replacement of the lateral attic wall, in one case a replacement of the total lateral attic wall, in one case a reconstruction of the canal wall after radical mastoidectomy, and in one case an obliteration of the mastoid cavity. These 25 ears have been followed up for 2-11 months with an average of 7,1 months. In 19 cases the implants showed no sign of any complication. In four cases, however, a dehiscence of the skinny covering (outer ear canal) was observed during the post-operative healing period. In one case this dehiscence closed spontaneously, in the other case we recovered the implant by surgery. In one patient we had to remove the implant, in another one the implant is uncovered and still under observation. An inflammation of the implant bed occurred once. One implant sank down into the middle ear cavity.

Animals↗

[Carcino-embryonic antigen and beta 2 microglobulin in malignant bone diseases. 61 cases (author's transl)].

Radioimmunological assays of carcino-embryonic antigen (CEA) and beta 2 microglobulin were carried out in 61 cases of malignant bone disease, including myeloma and metastases from carcinomas of the breast and prostate. CEA assays seemed to be of greater interest in mammary cancer metastases and beta 2 microglobulin assays in prostatic cancer metastases and myeloma. The correlation which appeared between CEA levels of the outcome of breast cancer metastases was of assistance in adjusting treatment. Combining CEA and beta 2 microglobulin assays would enhance their usefulness in current practice.

Beta-Globulins↗