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Biomedical subjects

C Berrut

Publications and source records attributed to C Berrut.

4 recordsLinked to original sources

[Pseudomembranous colitis caused by the ingestion of colocynth].

A 61-year-old woman presented with an acute condition involving confusion, abdominal cramps and bloody diarrhea six hours after accidental ingestion of colocynth mistaken for zucchini. Colonoscopic examination revealed pseudomembranous colitis though the patient had no condition known to be associated with pseudomembranous colitis. Within ten days the mental state returned to normal and the colitis resolved completely. It is suggested that the colitis was caused by the ingestion of colocynth.

Cathartics↗

[Gastroesophageal reflux and asthma].

Gastro-oesophageal reflux (GOR) occurs with increased frequency in asthmatics. GOR may cause pulmonary symptoms either by reflux of gastric contents into the trachea or by a reflex mechanism. Several studies have shown that the presence of acid in the oesophagus may induce slight bronchospasm. However, more recent studies have clearly demonstrated that acidification of the oesophagus may exacerbate the bronchial hyperreactivity characteristic of the asthmatic patient, thus rendering the patient more susceptible to bronchoconstriction by other stimuli. As some drugs used in the treatment of asthma decrease lower oesophageal sphincter pressure and thereby enhance GOR, a vicious circle may arise. As surgical and medical anti-reflux therapy has been shown to be effective in diminishing asthmatic symptoms in the asthmatic patient with proven GOR, 24-hour ambulatory oesophageal pH monitoring is recommended in order to detect such patients and give them a trial with an H2 receptor antagonist.

Asthma↗

[The role of ultrasonography in the diagnosis of diffuse liver disease].

131 patients thought to have diffuse liver disease underwent ultrasonography and percutaneous liver biopsy. The ultrasonographic criteria examined were hepatic echogenicity compared to that of the renal cortex, homogeneity of hepatic parenchyma, and regularity of hepatic outline. On the basis of histologic examination of liver biopsies, several groups of pathologic lesions (not diagnostic entities) were established. Evaluation of ultrasound and histology was double blind. When the lobular architecture of the liver was respected histologically (normal liver, granulomatosis, siderosis, hepatitis), the ultrasound was normal in 86% of cases. The sensitivity of ultrasound was 0.9 for detection of fatty liver and 0.6 for cirrhosis. An abnormal ultrasound predicted structural modifications or a fatty liver in 93% of cases. Ultrasound proved incapable of differentiating between fatty liver and cirrhosis.

Biopsy↗