Solitary tuberculoid hansen lesion of the ulnar nerve.
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Biomedical subjects
Publications and source records attributed to C Bhushan.
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Goats naturally infested with Damalinia caprae lice were used to evaluate the efficacy of flumethrin pour-on. The maximum load of lice infestation was detected in the neck region. The LC50 value of flumethrin pour-on against D. caprae was found to be 119.35 ppm and the 95% confidence limits were calculated to be 104.10 and 136.85 ppm. Flumethrin at the rate of 1 mg/kg body weight by pour-on application along the mid-dorsal line was found to be 100% effective in treating lice-infested goats compared with the control goats. The residual action of flumethrin was found to be at least 42 days during which period no apparent signs of any local or general adverse effects were observed. Based on these studies, it is suggested that flumethrin pour-on may be successfully used for both the prophylaxis and treatment of D. caprae infestation in goats and it is necessary to repeat the treatment after 42 days. The method of application is highly advantageous as it can be conveniently applied, even in animals with thick hair coat and during the winter months.
An extremely unusual "miliary" metastatic tumor of the brain in a 69-year-old man is reported. Although there was no known primary tumor, the patient had innumerable brain lesions involving both cerebral and both cerebellar hemispheres, the basal ganglia, and the brainstem. There was no associated edema, mass effect, or brain parenchymal reaction. None of the lesions showed any calcification.
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Sheep infected with a fenbendazole resistant strain of Haemonchus contortus and goats with a levamisole resistant strain of the same parasite were used to evaluate the anthelmintic efficacy of closantel. Closantel at the rate of 10 mg/kg body weight was 100% effective against the 2 resistant strains of the parasite as indicated by faecal egg count and worm reduction. The efficacy of fenbendazole in sheep and of levamisole in goats was 56.68 and 76.90%, respectively.
A rapid and simple method for concentrating leucocyte-free Babesia caballi-infected erythrocytes from in vitro cultures is described. Infected erythrocytes amounted to at least 95% of all red cells obtained.
Eighteen seven to 21-day-old crossbred (Bos taurus cross Bos indicus) calves were allocated to four groups (A to D). Groups A and B each consisted of six calves and groups C and D three calves each. Each calf in groups A, B and C was inoculated with ground-up tick supernate (GUTS) equivalent to two infected acini prepared from Theileria annulata-infected Hyalomma anatolicum anatolicum. Each calf in group A was also given a single intramuscular injection of buparvaquone, 2.5 mg kg-1 bodyweight simultaneously with GUTS, whereas each calf in group B was given a single intramuscular injection of long-acting oxytetracycline, 20 mg kg-1 bodyweight following inoculation of GUTS. In calves of group A clinicopathological reactions were negligible, whereas in calves of group B mild to severe reactions were observed resulting in the death of three of the six calves. All the calves of group C (infected, untreated controls) died of acute theileriosis. All the surviving calves of groups A and B withstood a lethal homologous challenge given on day 30 after immunisation, indicating no difference in the immune status of the surviving calves of the two groups. Group D, challenge control, all calves died of theileriosis within 18 days of challenge.
Twenty cross-bred (Bos taurus X Bos indicus) calves, 7-21 days old, were infected by a ground-up tick supernate of Hyalomma anatolicum anatolicum infected with the Hisar isolate of Theileria annulata. Six calves acted as untreated controls and they all died of theileriosis within 17 days of infection. The remaining 14 calves were divided into Group A and B, each consisting of seven calves. All the calves of Groups A and B were treated intramuscularly with buparvaquone (BW 720C) on Day 11 post-infection, when clinical signs of theileriosis were apparent. Each calf received 2.5 mg BW 720 C kg-1 body weight as a single injection. In addition, each calf of Group B was given proprietary haematinics by intramuscular injection, daily for 12 days. In Group A, two calves died of cerebral theileriosis and five were clinically cured. However, four of these five calves later died of anaemia. In Group B, all the calves were clinically cured and none died during the observation period of 1 month. The parasitaemia declined to less than 1% within a fortnight of treatment. The initial declines in haemoglobin concentration and packed cell volume were halted and preinfection values were soon restored. No toxic signs attributable to treatment with buparvaquone were observed.
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Sixty three cross-bred (Bos taurus X Bos indicus) 4-5-day-old calves were divided into 16 groups (A-P). Each calf in Groups A and B was given ground-up-tick supernate prepared from Theileria annulata-infected or non-infected Hyalomma anatolicum anatolicum (GUTS) equivalent to 5 ticks (50 infected acini). Groups D and E received infected GUTS equivalent to 2 ticks (20 infected acini) and Groups G and H were given infected GUTS equivalent to 1 tick (10 infected acini). Each calf in Groups J, K and L received infected GUTS equivalent to 5 infected acini (0.035 tick), and Group O was inoculated with non-infected GUTS equivalent to 5 ticks. Each calf in Groups A, D, G, J, K and O was also given a single intramuscular injection of long acting oxytetracycline, 20 mg kg-1 body weight just after inoculation of GUTS. Severe reactions resulted in the death of five of eight, three of eight, five of six, one of five and one of five calves in Groups A, D, G, J and K respectively and all of the calves in Groups B, E, H, and L. The surviving calves of Groups A, D, G, J, K and O were challenged on Day 45 post-immunization along with freshly introduced susceptible control calves of Groups C, F, I, M, N and P. All the calves of Groups A, G, J and K withstood the challenge dose; in Group D four of five and in Groups C, F, I, M, N, O, and P all the calves died of theileriosis. It is concluded that though the infection and treatment method of immunization may be used for neonatal bovines, the dose of immunogen should be based on actual counts of infected salivary acini of ticks instead of the number of ticks.
Four additional cases of synovial cyst (ganglion) arising from the facet joint between L4 and L5 are reported. Only five such cases have been reported in the past. For the first time impressive and characteristic myelographic findings are described, which make a preoperative diagnosis possible in these cases.
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Results of postoperative peritoneal lavage using balanced saline and antibiotic solution in 30 patients with diffuse peritonitis have been presented. The results of this study show that such lavage is a significantly useful adjunctive treatment in the management of diffuse peritonitis. It appreciably reduces the mortality and morbidity. Its adjunctive use in suitable cases along with surgery can be safely advocated in clinical practice.
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