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Biomedical subjects

C Billerey

Publications and source records attributed to C Billerey.

47 records · Page 3Linked to original sources
PubMed1984

[Nephrogenic metaplasia of the urothelial mucosa. Apropos of 11 cases].

The authors report eleven new cases of nephrogenic metaplasia - a substantial addition to the sixty-three cases already reported in the literature. In their series, two cases involved the ureter, and nine, the bladder. They discuss the clinical and pathological aspects of the disease, and put forward suggestions concerning different aspects of the histogenesis. They consider the possibility of introducing new terminology.

Adolescent↗
PubMed1984

[Laryngeal leishmaniasis in a patient from the Jura. Unusual cause of epitheloid and giant cell granulomatosis].

A case of laryngeal leishmaniasis in a patient living in eastern France is reported. Mucosal leishmaniasis appears to be frequent in the New World but rare in the Old World, where only 9 cases have been published, including 3 from France. In this particular patient, there probably was some relationship between the laryngeal lesion and an unexplained malaria-like fever contracted in Algeria 19 years before. This case provides evidence that leishmaniasis is one single nosological entity throughout the world, its different clinical forms (cutaneous, mucosal, visceral) merely reflecting the adaptation of the parasite to its environment.

France↗
PubMed1983

[Histoprognostic factors of non-infiltrating urothelial tumors of the bladder].

The authors reported a pathology and clinical study about 215 cases of non infiltrating transitional cell carcinoma of the bladder. During the successive treatments of these lesions 475 specimens were collected. 5 tumours characteristics were analyzed: size of the tumour, multiplicity, microscopic structure, grade, mitotic index. The average time of supervision was 39,6 months. 75% of the patients presented a tumour recurrence over the 5 years period and in 3% of the cases deaths were directly attributable to the tumour. Multiplicity and especially mitotic index are the only tumour characteristics which correlated well with the likelihood of new tumour occurrence. The grade and the mitotic index are the best criteria to assess the risk of recurrence as an infiltrating carcinoma. The distribution of tumour characteristics shows that this type of lesion roughly keeps the same pathological pattern during recurrences. Nevertheless there exists a cellular dedifferentiation trend as well as an increase of mitotic index.

Adult↗
PubMed1982

[Primary vesical adenocarcinoma with signet ring cells or linitis plastica of the bladder. Three cases].

Signet ring cell adenocarcinomas of the bladder are regarded as rare tumours. The authors actually think that their frequency is underrated since they report three new cases out of a range of 700 bladder tumours. Revealing signs consist in urgency pain, frequency and/or hematuria. This set of cancer is usually tardily diagnosed and therefore of very poor prognosis whatever the therapies.

Adenocarcinoma, Mucinous↗
PubMed1982

[Nephroblastoma in the adult. Apropos of a case].

Nephroblastoma is a rare tumour in the adult and the diagnosis is only rarely made preoperatively. In the light of a new case, the authors consider the problems of histopathological differential diagnosis with other borderline forms. They study the clinical aspects of these tumours. The prognosis would seem to be extremely gloomy, worse than that of renal adenocarcinoma.

Adult↗
PubMedDate not supplied

Influence of cigarette smoking on P53 gene mutations in bladder carcinomas.

BACKGROUND: The aim of this study was to analyse the influence of cigarette smoking on bladder carcinomas. PATIENTS AND METHODS: 98 cases of bladder cancers were examined by single strand conformation polymorphism analysis of exons 5 to 9, followed by DNA direct sequencing. RESULTS: The incidence of p53 gene mutations was not significantly influenced by habitual smoking. However, the p53 mutation spectrum of current smokers differed significantly from the pattern for non-smokers and ex-smokers. Differences between the two populations included multiple mutations in the current-smokers and an absence in non- and ex-smokers (p<0.01), with the predominance of G:C to A:T transitions at CpG sites in non-smokers (60.0%) in comparison with current smokers (7.6%) (p<0.02). Moreover, G:C to T:A and G:C to C:G transversions were found solely in current smokers. CONCLUSION: It would appear that, in current-smokers, the spectrum of p53 gene mutations is related to tobacco-smoke carcinogens and that the habit of smoking increases the extent of DNA damage.

Aged↗