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Biomedical subjects

C Bonnard

Publications and source records attributed to C Bonnard.

17 recordsLinked to original sources
PubMed1992

[Experimental study of primary fixation of screw-ring acetabular components. Role of initial screw-cutting].

Three types of screw-ring acetabular components were implanted to determine the characteristics of their holding power and to study the influence of screw-cutting. The acetabular components were screwed into vinyl polychloride foam. Their resistance was measured. The optimal value of the locking screw couple and the value of the couple beyond the one at which the acetabular component loosened were determined. One of acetabular components was screwed in with and also without preliminary screw-cutting. Its resistance to wrenching was measured in both situations. The resistance curve at wrenching was characteristic of each screw-ring acetabular component. The resistance to wrenching was significantly higher (p < 0.01) for a given acetabular component if it was screwed into a largely open block of foam at its bottom. The screw-cutting allowed for a significantly higher resistance to wrenching (p > 0.05). It allowed for the screwing in with the least effort and for a better perception of the tightening. Knowledge of the comportment of screw-ring acetabular components once installed, usage of preliminary screw-cutting and recourse to a dynametric key are the means of improving the installation of screw-ring acetabular components.

Acetabulum↗
PubMed1992

[Carpal tunnel syndrome].

The carpal tunnel syndrome is very frequent. The authors insist on some points of surgical technique. The results of a Swiss study on the problem of the recurrent carpal tunnel syndrome are described (96 cases); the etiology of the recurrency, the surgical technique and the results after operative revision are analysed.

Carpal Tunnel Syndrome↗
PubMed1991

Late lesions of the brachial plexus after fracture of the clavicle.

Fractures of the clavicle, particularly those which are markedly displaced, may, in rare instances cause injury to the subclavian vessels and the brachial plexus which manifest progressively days or weeks after the initial trauma. More often than not, however, a costo-clavicular compression syndrome appears months or years after the clavicular fracture as a result of constriction by scar which invests the neuro-vascular bundle, by a secondary aneurysm or by hypertrophic callus. The authors report 16 such cases, one of which was treated conservatively, thirteen treated by surgical intervention while two cases are awaiting operation. These patients represent just over 1% of brachial plexus lesions seen over a period of twenty years in two surgical centres. Operative treatment consists of reduction of the clavicular deformity, possibly first rib resection, liberation of the plexus and correction of a vascular lesion as required. The outcome is usually good.

Adolescent↗
PubMed1991

[Surgery of the lower limbs in Duchenne's muscular dystrophy].

Seventy-one children had surgical procedures on hips and/or knees and/or feet contractures before or after the age of loosing gait. Gait has been continued on 1 year and 7 months to 3 years and 8 months according to the evolving type of Duchenne Muscular Dystrophy (DMD). After analysis of results of the surgery upon contractures, surgical procedures have been determined for each joint. Before loosing gait, but when contractures were all present, surgery prolonged on gait without orthosis and relieved of physiotherapy. During the 6 months after loosing gait, surgery allowed to recover same walking ability more often with orthesis. After loosing gait, surgery gave a better comfort of life to the child and his family.

Child↗
PubMed1991

[Reinhardt-Pfeiffer mesomelic dysplasia or dyschondrosteosis? Is the distinction well-founded? Apropos of a familial case with variable expression].

A familial observation of Reinhardt-Pfeiffer type mesomelic chondrodysplasia spanning three generations is reported. This case clearly shows that expression of the disease can vary widely within a given family. One member affected as a fetus had a severe form suggesting Langer mesomelic dwarfism syndrome, whereas his mother was free of clinical symptoms and his maternal aunt had a typical form of Reinhardt-Pfeiffer syndrome. Clinical manifestations in the other affected family members were perfectly consistent with dyschondrosteosis syndrome. The very broad spectrum of clinical patterns in this family suggests that there may be connections between the various types of mesomelic dysplasia. Establishing clear-cut distinctions between these entities, although useful in practice, may not accurately reflect molecular anomalies. Furthermore, the family member affected as a fetus also had Turner syndrome, which may have contributed to the severity of his condition. The possibility of identifying severe mesomelic dysplasias antenatally by ultrasonography should be pointed out.

Acrocephalosyndactylia↗
PubMed1990

[Patellar instability in children. Result of transposition of the medial third of patellar tendon].

Before bony maturity, the treatment of the recurrent dislocation of the patella is based on tendinous transfers. These distal procedures were often combined with proximal procedures on the medial or lateral patellar retinaculum and vastus medialis muscle. For the purpose of analysing efficacity of the medial third tendon transfer to the distal and deep part of the medial collateral ligament before the bony maturity, 24 children have been reviewed with a post operative follow up of 14 months to 6 and half years. There were 4 boys and 20 girls between 7 to 15 years old at the time of surgery. The troubles duration before the operation was from a few days to 4 years and the pathology was very often bilateral (40 knees). The recurrent dislocation of the patella was present 6 times, an instability 25 times and a traumatic dislocation 9 times. The technical procedure was every time a stabilisation with the transfer of medial third of the patellar tendon, associated except in 6 cases with a correction of the patellar motion by patellar retinaculum plasties. The functional result has been evaluated according to the sport activity and the ordinary life, with very hard criteria according to patient's age. Twenty-four times the result was excellent (60 per cent), 8 times good (20 per cent) and fair 8 times. Two complications have been observed. The improvement of the trochlea angle, and the trochlea deepness have been significant. Sixteen patients (27 knees) have been reviewed after the bony maturity and no growth disturbance of the tibial tuberosity has been observed.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1989

[Osteoarthritis of the hip in children. Proposal for a classification of sequelae guiding therapeutic indications].

Twenty-six hips in 21 patients were available at mean follow up of 5 years in a retrospective functional and radiographic analysis for the purpose of examining the late effects of infantile septic arthritis. Poor results after reconstructive efforts following hips joint sepsis suggest help classification of bony deformation. Epidemiologic and clinical findings were analysed. Late diagnosis and prematurity were found as poor forecast facts.

Acute Disease↗
PubMed1988

Effects of palytoxin or ouabain on growth and squamous differentiation of human bronchial epithelial cells in vitro.

The effects of the non-12-O-tetradecanoylphorbol-13-acetate type tumor promoter palytoxin on human bronchial epithelial cells was studied in an in vitro serum-free culture system. Unlike the results of previous studies with another tumor promoter, 12-O-tetradecanoylphorbol-13-acetate, palytoxin did not induce squamous differentiation of normal bronchial epithelial cells and was equally cytotoxic for normal human bronchial epithelial cells, a human lung tumor cell line, and human bronchial epithelial cells immortalized by infection with adenovirus 12-SV40 hybrid virus (BEAS-2B cells). Palytoxin did not induce a change in free cytosolic Ca2+ concentration of BEAS-2B cells. The effect of palytoxin on the c-myc mRNA steady state level in BEAS-2B cells was studied: 1 pM palytoxin increased the steady-state level at 12 and 18 h. Furthermore, the induction was accompanied by an increase in [3H]thymidine uptake. Because palytoxin binds to (Na+ + K+)ATPase, the effects of ouabain were compared to the effects of palytoxin. A ouabain-resistant cell line was as sensitive to the growth inhibitory effect of palytoxin as the parent ouabain-sensitive cell line, suggesting different binding sites to the (Na+ + K+)-ATPase for palytoxin and ouabain. Ouabain also increased the steady-state level of c-myc gene expression, but earlier than palytoxin, and the increase in the level of c-myc mRNA was accompanied by a drop in DNA synthesis. These results suggest that palytoxin does not act by growth stimulation, differential cytotoxicity or terminal differentiation of normal versus neoplastic cells which are proposed mechanisms of tumor promotion.

Acrylamides↗
PubMed1986

The cervico-thoracic outlet compression syndrome. Analysis of surgical treatment.

Surgical treatment of the thoracic outlet compression syndrome is being presently reconsidered. Until these last few years, there was the choice between two interventions only: scalenotomy, a simple operation entailing no complication, but with a 60% recurrence rate--or the resection of the first rib through an axillary approach, an efficacious intervention which caused, however, serious nervous complications in 14% of treated cases. The follow-up of 75 cases operated for a TOCS reveals to the authors that--all techniques taken into account--results are unsatisfactory in 33% of cases. These failures are due either to technical deficiencies, or to a complication arising in the course of the operation, or to an erroneous diagnosis. The authors resort to surgery only to treat serious vascular syndromes (absolute indication) or invalidating neurological compression syndromes, after failure of physical therapy (relative indication). They propose a cervical approach--the only one enabling a safe dissection of the brachial plexus--a partial scalenectomy, resection of all fibrous bands pressing on nervous trunks, or the resection of a cervical rib. Should the costo-clavicular space appear anatomically too narrow, the first rib, already partially freed by the cervical approach, will be resected through the axillary route.

Diagnosis, Differential↗
PubMed1986

[Paralysis of intrinsic muscles of the hand in lesions of the brachial plexus].

240 patients out of 752 seen over a period of 21 years with traction lesions of the brachial plexus including a palsy of the intrinsic muscles of the hand have been studied by the authors. This study is biased by a high number of imprecisions. Nevertheless it shows that the fate of the intrinsic muscles depends essentially on the initial severity of injury whatever the type of conservative or operative treatment. There is no useful recovery when the lesions of these pathways are more severe than the 2nd degree of Sunderland. Palliative surgery is indicated in cases when all muscles of the forearm have reached a good function after conservative or operative treatment. Reconstructive surgery is however limited or prone to fail in 2/3 of cases because in the vast majority of patients with traction lesions of the brachial plexus there is no recovery of wrist and long finger extensors.

Brachial Plexus↗