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Biomedical subjects

C Bourdalle-Badie

Publications and source records attributed to C Bourdalle-Badie.

9 recordsLinked to original sources
PubMed1996

Cognitive sequelae of propofol anaesthesia.

As with any substance that interferes with nervous system functioning, anaesthetics are likely to have neural effects the duration of which extend beyond the acute loss of consciousness. Studies of recovery after anaesthesia have shown that physiological effects and psychomotor functions return to pre-anaesthesia levels within at most 90 min of the cessation of propofol administration. To date no report has been published concerning the possible longer term effects of propofol anaesthesia on higher cognitive functions such as learning, language, reasoning and planning. We evaluated a range of cognitive tasks (short and long-term memory, attention, language comprehension and planning) up to 6 h after cessation of Propofol administration, and found that this set of cognitive functions was still depressed after 3 h, but had recovered by 6 h. The results suggest that, for their security, patients should be remain in a supervised environment for at least 3 h after propofol anaesthesia, and that oral information to patients within those 3 h should be avoided.

Adolescent↗
PubMed1989

[Anesthesia for extracorporeal lithotripsy in the treatment of renal lithiasis].

Extracorporeal shock wave lithotripsy has become the main technique for treating renal lithiasis. It has many repercussions on anaesthesia. The fundamental technical concepts of lithotriptors are reviewed. The problems due to the different systems (electrohydraulic or piezoelectric--the most widespread in France) are discussed. Electrohydraulic systems, which are more adapted to the treatment of large stones (diameter greater than 2 cm), require the immersion of the patient. As a result, there are analgesic, cardiovascular, respiratory and temperature repercussions on the anaesthetic management of these patients. General anaesthesia is generally more appropriate for this technique. On the other hand, piezoelectric systems are more adapted to the treatment of medium-sized or small calculi (diameter less than 2 cm), and do not require immersion. Anaesthesia is often not required for the use of this technique, but, if necessary, local, regional or general anaesthesia may be used. For either technique, the anaesthetic protocol must be adapted to the patient's and the surgical indications.

Anesthesia↗
PubMed1980

[Long-lasting anaesthesia. Advantages of electroanaesthesia (author's transl)].

In a series of 15 anaesthesias lasting more than 8 hours, the authors completely replaced morphine-like drugs with the use of electric currents; the method used was that recommended by Professor Cara and his team. The low toxicity of this technique, alertness on waking and degree of post-operative analgesia are stressed; the possibility of mobilisation of naturally occurring morphine-like substances is raised, considering recent neurophysiological work. This leads the authors to refer to electric analgesia rather than electric anaesthesia.

Adult↗
PubMed1975

[Autotransfusion in experimental hemoperitoneum. Hematologic study].

In order to study the hematologic repercussions of pre-operative autotransfusion, ruptures were made in experimental spleens followed by retransfusion after intraperitoneal barbotage of long duration in 8 dogs. This was performed without any heparinization. The following facts could be established:--although the blood shed was rich in red globules, it presented major alterations with a loss of clotting agents and evidence of fibrinogenic degradating elements.--A study of the blood during the transfusion and after the intervention did not reveal any intravascular coagulation but only a loss of fibrinogen and thrombocytes proportional to the amount of autotransfused blood. The limit of haemostatic tolerance with no supply of external blood was an autotransfusion ranging about 75 p. 100 of the initial blood volume.

Animals↗
PubMedDate not supplied

[Reversible acute hepatic failure after treatment with association of isoniazide-rifampicin (author's transl)].

One case of severe acute hepatic failure happening after surgical treatment of large tuberculous ureteral stenosis is reported. The etiology was the association of isoniazide-rifampicin; the clinical, biological and histological data of these hepatitis cases are specified; their physiopathology, as well as their treatment is studied; prevention by plasmatic evaluation of isoniazide is especially important.

Acute Disease↗