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Biomedical subjects

C Bowen

Publications and source records attributed to C Bowen.

28 records · Page 2Linked to original sources

Prematurity and the obstetrician. A regional neonatal intensive care nursery is not enough.

Modern-day perinatal care has resulted in dramatically improved outcomes of premature infants, particularly those weighing 750 to 1,500 gm or of 27 to 32 weeks' gestational age. Assuming that the birth is not traumatic, the infant asphyxiated, or made hypothermic at birth, the chances of the very small premature baby developing normally are great. The delivery of an infant of less than or equal to 32 weeks' gestational age or weighing less than 1,500 gm should occur at a perinatal center when possible.

Delivery, Obstetric↗

Trypanosoma cruzi isoenzyme variability in Ecuador: first observation of zymodeme III genotypes in chronic chagasic patients.

We have analysed by multilocus enzyme electrophoresis (MLEE) at 21 genetic loci 10 Trypanosoma cruzi stocks isolated from chronic chagasic patients and 3 stocks isolated from Triatoma dimidiata collected in human habitats from the coastal part of Ecuador (all stocks isolated in August-December 1998). Isoenzyme profiles were compared to those of 4 laboratory-cloned stocks representing the major phylogenetic subdivisions of T. cruzi. This parasite's genetic variability in Ecuador proved to be considerable, even in this limited sample, since all main isoenzyme genotypes were recorded. Four stocks from patients were identical at all loci to the reference stock MNcl2 ('major clonet #39'; T. cruzi II) isolated in Chile. The 3 stocks isolated from T. dimidiata were closely related to the formerly described zymodeme I (T. cruzi I). Finally, 3 stocks from chronic chagasic patients (one with an asymptomatic form, 2 with a cardiac-digestive form) were closely related to the formerly described zymodeme III (presently not classified in either T. cruzi I or T. cruzi II). This is the first observation of this category of T. cruzi genotypes in chronic chagasic patients. In the past it was recorded only in acute patients, wild mammals and wild triatomine bugs. The epidemiological implications of these results are discussed.

Adult↗

School survey highlights teenage problem areas.

The health of the Nation highlights the need to reduce suicide rates among young people. A multidisciplinary group sought to adopt an approach to promoting mental health which began with young people's own concerns. Via a questionnaire to 80 14-15 year olds the group established that young people had particular worries around self-esteem and self-image, family and personal relationships, loss and bereavement and teacher/parent expectations. These issues are now being addressed within a resource pack soon to be published.

Adolescent↗