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Biomedical subjects

C Buchan

Publications and source records attributed to C Buchan.

5 recordsLinked to original sources
PubMed1985

Surgical resection of a pineal tumor containing elements of germinoma and astrocytoma.

A 15-year-old boy presented with hydrocephalus due to a pineal tumor presumed to be a germinoma. After a shunting procedure, gross total tumor resection was carried out via an occipital transtentorial approach. Histopathological examination of the tissue demonstrated that, in addition to the expected germinoma, the tumor also contained areas of astrocytoma and areas that, taken in isolation as in a needle biopsy, could have been diagnosed as pineocytoma. The diagnosis and therapy of a pineal tumor of mixed histological types such as this lesion would be seriously compromised by "conventional" empiric radiation and even a stereotactic needle biopsy may not have provided an adequate tissue sample.

Adolescent↗
PubMed1985

Late stenosis of a superficial temporal-middle cerebral artery bypass: angiographic and histological findings.

The course of a patient with an initially widely patent superficial temporal artery-middle cerebral artery (STA-MCA) bypass and an enlarged donor vessel is presented. Over 17 months, the STA became markedly stenotic. Serial angiography is correlated with autopsy histological findings showing severe atherosclerotic changes throughout the donor vessel. The potential causative factors, both medical and surgical, are discussed and the appropriate literature is reviewed. Parallels are drawn from the cardiac bypass experience. The bypass itself may have precipitated or accelerated intimal hyperplasia, which stenosed (and may have eventually occluded) the vessel. Is this phenomenon more frequent than we realize?

Cerebral Angiography↗