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Biomedical subjects

C Burcoveanu

Publications and source records attributed to C Burcoveanu.

At least 19 recordsLinked to original sources
PubMedDate not supplied

[Insulinemia and its evolution over time in obesity].

There is a steady-state metabolism of adipose tissue ("adipose state") with a "metabolic signal" significance. It consists of: seric levels of glucose, insulin, free fatty acids. We studied 45 cases with uncomplicated obesity and we correlated seric level of insulin, basal and reactive, with DAM (mean adipocyte diameter), insulin receptor activity and obesity evolution length (age of obesity). Level of insulin has high influence on insulin receptor function (p < 0.01). Reactive insulin level are higher with obesity age (p < 0.0001). Hyperinsulinemia is a constant, continuous and early reference point of obesity.

Adipose Tissue↗
PubMedDate not supplied

The anatomical variants of the profunda femoris artery and of its collaterals.

The profunda femoris artery, the main nutritive artery of the thigh, has a great surgical significance. The high frequency of the occlusive arterial disease in the lower limbs caused by atherosclerosis, imposes as main therapy the reconstructive surgery. Because the profunda femoris artery remains patient in most of the cases of the occlusive arterial disease of the lower limbs, it means the only hope of saving an critically ischemic limb in a desperate attempt of a surgeon to avoid amputation.

Arteriosclerosis↗
PubMedDate not supplied

[Therapeutical options in partial infected aorto- bifemoral prosthetic grafts].

PURPOSE: To asses the use of synthetic or autologous conduits for the reconstruction of iliofemural sector in the cases of partial, limited infections of aortobifemural prosthetic grafts. METHOD: We present two cases, both of them with infection recognized at the groin; the first one by a vascular fistula bleeding intermittently, the second by a draining groin sinus with fever and leukocytosis. RESULTS: The PTFE conduit was the material utilized at the first case and the superficial femoral vein in the second case. The patients presented completed resolution of the infectious signs and symptoms and the revascularisation of the legs was successfully done. Evan with an extra-anatomical bridge or an autogenous material, sometimes is possible to resolve a regional infection of the aortobifemural graft only with a partial resection of one leg of the prosthesis and replacing with another sterile material.

Acinetobacter Infections↗
PubMedDate not supplied

[Surgical treatment of hepatocellular carcinoma--indications, limitations, realities].

The present study analyzes the importance of the factors in improving the resectability, obtaining morbidity and mortality rates in accordance to the actual exigencies. In The III-rd Surgical Clinic, "Sf.Spiridon" Hospital, Iaşi, during 1998-2003, 24 cases of CHC (19 men, 5 women with a median age of 58.5 years), usually developed on a cirrhotic liver, benefited by surgical approach. The tumoral mass (median size 7.8 cm) was situated in the left liver (15 cases--62.5%), right liver--13 cases and for 1 case with multiple localization (the segments VI-VII and III). For 12 cases (50%) various extensions of liver resections have been undergone: left lobectomies II-III--4 cases, left hepatectomy--1 case, segmentectomies VI--3 cases, segmentectomy III + bisegmentectomy VI-III--1 case, atypical hepatectomy--3 cases. Only 2 cases benefited by right portal vein ligation prior to resection. In 12 cases intraoperative exploration and US examination (4 cases) contraindicated the resection. One patient deceased on the entire lot (4.16%); post-resection mortality--8.33%. In conclusion, the early diagnostic of CHC developed on cirrhotic liver, the patients selection, the use of laparoscopy and intraoperative US, the available devices (CUSA dissector), selective ligation of portal branch prior to resection represents imperative elements in improving the resectability in safe conditions for the patient.

Adult↗
PubMedDate not supplied

[Spontaneous esophageal rupture in three patients].

Boerhaave's syndrome represents the most severe perforation of the gastrointestinal tract. The typical clinical presentation is by a sudden onset of pain after a vomiting effort on the background of an alimentary and alcoholic abuse. It usually associates the cervicomediastinal emphysema, altogether forming the Mackler triad. The atypical presentation and the rarity of this entity usually lead to the delay in diagnosis in 50% of the cases. The diagnosis requires native and hydrosoluble contrast radiological examination which may reveal, altogether with the esomedistinal or esopleural fistula, pneumomediastinum, cervical subcutaneous emphysema, pleural effusion or hydropneumothorax. The early diagnosis and surgical treatment in the first 24 hours after the perforation offer the best chances for survival. We present and analyze the cases of 3 patients with spontaneous esophageal rupture with their different evolution and the diagnostic and treatment steps in each case.

Aged↗
PubMedDate not supplied

[Spontaneous rupture of the esophagus. Case report].

We present a 50 years old man who was admitted for severe pain in the chest appeared after vomiting, dyspnoea, cardiovascular collapse. The diagnosis of spontaneous perforation of the esophagus (Boerhaave's syndrome) was confirmed by a radiopaque swallow. We performed a laparotomy, mediastinal drainage, cervical esophagostomy and jejunostomy. Postoperatively, the general state was severe--with high fever, important pleurezia, necessitating pleural drainage, mechanical ventilation for 8 days, parenteral and jejunostomy nutrition. It was possible to close the esophagostomy in the 43rd postoperative day. The patient has been dismissed on the 59th day. Five days later he presented in the ER with severe dyspnoea due to tracheal stenosis--emergency tracheotomy was performed, followed by resection of the stenotic cartilages.

Esophageal Diseases↗
PubMedDate not supplied

[The diagnosis and treatment of benign tumors of the subdiaphragmatic digestive tract].

One hundred twenty-two benign tumors of subdiaphragmatic digestive tract admitted in the interval 1975-1988 at the III-rd Surgical Clinic of Iaşi are reported. Out of these patients 120 required surgical treatment, the remainder of 2 being treated conservatively (diffuse intestinal angiomatosis, Peutz-Jeghers' syndrome). The clinical evolution being atypical, the surgical intervention was required, in most of the cases, due to hemorrhagic and occlusive complications. Histologically, the polyps and schwannomas were prevalent. The diagnostic difficulties, especially in the cases with jejuno-ileal localization, are mentioned.

Diaphragm↗
PubMedDate not supplied

[The clinical, diagnostic and therapeutic characteristics in antral gastric cancer].

This paper is part of a comprehensive study on subphrenic digestive cancer carried out between 1984 and 1988, representing the experience of the III-rd, I-st, IV-th and emergency surgical clinics of Iaşi (1530 cases). The peculiarities of gastric cancer with antral site in 231 out of a total of 612 cases, representing the experience of the III-rd Surgical Clinic, are presented. Clinically, the relative early occurrence of the symptoms, the need for an endoscopic examination and biopsy for all gastric ulcer lesions, for the antral ones particularly, are mentioned. The treatment is surgical, but it has to be associated with adjuvant therapy. For the antral site, the oncological subtotal gastrectomy was the surgery of choice (157 cases), the need of restoring the transit in a gastrojejunal manner being underlined. Total gastrectomy was performed in 12 cases.

Combined Modality Therapy↗
PubMedDate not supplied

[Bronchial asthma in old people].

Bronchial asthma in old people is defined, according to a number of Anglo-Saxon authors, as a disease which occurs for the first time (de novo) at an advanced age (i.e. over 70 years). The present follow-up study had been carried out in the Diagnostic Division of the Outpatient Department--Polyclinic no. 1 of Iaşi--and has in view only the patients who had the first attack of disease at the time they were over 60. Clinical examination was complemented by the following tests: spirography, X-ray, allergological cutaneous tests, and test for the identification of eosinophils in sputum. A certain pattern was identified: the first asthmatic symptoms followed rhinobronchial episodes persistent spasmodic cough and continuous dyspnea induced by effort were frequent complaints; typical crises were uncommon. The allergic aetiology was supported by a positive anamnesis, while the cutaneous tests confirmed the presence of an allergen in only 20% of the cases; chronic and recurrent infections were present in 85% of the cases. At the same time, the presence of gastroesophageal reflux was searched as its frequency in the elderly as well as its role in inducing the bronchial asthma have often been reported. It is expected the identification of the characteristic pattern might lead to a correct diagnosis of bronchial asthma in old people and contribute to better therapy.

Aged↗
PubMedDate not supplied

[Bacteria detected in the duodenal aspirate of patients with biliary tract disorders].

In 614 patients with pains in the right hypochondrium the cyto-bacterioscopy and bile culture were performed. In 575 patients bile samples were obtained by sterile catheterization and in 39 patients by biliary tract puncture during surgical intervention. It resulted that for a reliable cyto-bacterioscopic examination and its agreement with bile culture results it is necessary to investigate only the samples with pH greater than or equal to 5 and during the first two hours after their collection. The isolated bacterial species can be considered to be etiologic agents of the biliary infection depending on the following parameters: significant quantitative threshold of minimum 10(5) colony forming units per milliliter, presence of inflammatory reaction and activity of the gastric acid barrier.

Bacteria↗