[Herpetic keratitis and corneal grafting].
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Biomedical subjects
Publications and source records attributed to C Burillon.
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This study attempts to better define band keratopathy. A total of 23 eyes were reviewed, the largest sample ever published. The histopathology of this condition, characterized by lesions situated beneath the corneal epithelium, as well as its various clinical forms, are described. A distinction is drawn between band keratopathy and brown band keratopathy from an etiological and histological standpoint. The various available treatments are reviewed, emphasising lamellar keratoplasty as the safest and most effective technique.
The analysis of 56 successive procedures for correction of severe myopia enables us to determine the indications of the two surgical techniques we use: Myopic keratomileusis or Myopic Epikeratophakia. The results are very different. They are reliable and steady throughout one year for certain myopias, but more uncertain for more severe ones. This led us to distinguish two subgroups: the first includes the initial myopia equal to or less than -15 dioptres, the second includes the more severe myopia. Epikeratophakia, always implemented using fresh lenticules corrects more severe myopias than keratomileusis (from -15 to -30 dioptres). So, the indication for epikeratophakia depends on the initial ametropia, as well as on refractive parameters such as keratometry. With the same myopia, an anterior curvature radius over 8.2 mm will render a myopic keratomileusis less efficient then a myopic epikeratophakia. The results with one year follow up are more predictable and stable for the first subgroup. The second group and those cases corrected by epikeratophakia had less predictable results.
The authors present the results of a series of 200 radial keratotomies. there were two anatomical complications, neither of which caused any clinical damage. 83% of patients obtained 5/10 distant visual acuity or more without correction. The overcorrection rate was 1.5%. The incidence of induced astigmatism was 3.0%. The real failure of the method lay in an undercorrection rate of 13%. These cases are analysed here. Correction proved easier as patients were older: 0.64 diopters per decade. There was a 0.30 diopter gain in men over women. With corneal curvature of more than 43.5 diopters, the benefit was 0.15 diopters per diopter of keratotomy. Limbus to optical zone incisions provided 1.60 diopters as compared with optical zone to limbus incisions, while redeepening incisions provided only 0.27 diopters. Emphasis is placed upon practical matters, such as quality of measurement, instruments and the dexterity of the surgeon. We limit surgical indications to within the range of -1.50 diopters to -4.50 diopters of myopia. The undercorrection rate within this myopia range was 6.3%, increasing to 39.0% over the range.
A woman-aged 44-had corneal dystrophy anterior to Descemet's membrane. This corneal abnormality resembles Cornea Farinata with tiny, punctate, grey opacities localized in the entire thickness of the corneal stroma. We used light and electron microscopic to study this case. The corneal opacities were due to abnormal stromal keratocyte enlarged by intra-cytoplasmic vacuole containing lipid-like inclusions.
The authors analysed the results of 24 patients who underwent non-freeze refractive surgery with the BKS set. 22 myopic and 6 hypermetropic keratomileusis, and 6 epikeratoplasty are evaluated. The majority of patients had no astigmatism (or some irregular one) on corneoscopy. The final refraction may take up to 6 months to stabilize. The technique is difficult but may have application in the visual rehabilitation of these patients.
Surgical rehabilitation of the eye following severe burns is difficult and frequently leads to failure. Penetrating keratoplasty gives functional improvement which is often of short duration because of recurrence of the epithelial defect or because of the gravity of the initial injury. A method which includes a first step before corneal transplantation is described: a lamellar corneo-conjunctival autotransplantation, from the uninjured fellow eye is performed in order to improve the epithelial condition of the injured eye prior to later penetrating keratoplasty. This lamellar graft was performed on 25 patients between 1984 and 1988. Analysis of the results demonstrates the efficacy of the method: no complications were noticed on the grafted or the uninjured eye; visual acuity was improved in 76% of cases; the following penetrating keratoplasty led to a good result (clear graft at one year) in 88% of cases; and in 16% of cases, functional improvement gained with this first surgical step was sufficient to avoid having to carry out the penetrating keratoplasty.
After remembered the symptoms of Scheie syndrome, we described an original observation of two brothers affected by this disease and reported the histologic and electronic studies. Then, we tried to define the reasons of keratoplasty failure.
This study divides major astigmatism into 2 groups for which the authors advocate a new type of wedge resection. Group I includes 18 patients with astigmatism occurring as a complication of penetrating keratoplasty. Group II includes 10 patients with astigmatism due to circumscribed peripheral limbal corneal dystrophy. Wedge resection over a 180 degrees corneal arc resulted in a significant reduction of preoperative astigmatism and an improvement of visual acuity. Use of a photokeratoanalysor could permit better prediction of the expected effect of wedge resection. This instrument provides measurements of all corneal parameters necessary for determining whether surgery should be performed and which technique to use.
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The case of a young woman with an unilateral corneal edema with regular folds of the descemet's membrane is reported. These lesions originate from an obstetrical traumatism by forceps and are associated with cutaneous scars of the temples. Scanning electron microscopy of the cornea shows multiple endothelial fissures; they are responsible for the late corneal decompensation.
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Indications of enucleation for uveal tumors were systematic in the past. They should become more adapted actually. Anterior limited uveal tumors, as in our two personal observations, should be an indication to realize a preservative treatment of the eye; the authors recommend the "block-excision" method, which allows: first, the ablation of the whole tumor and consequently the best possible prognosis, then, an anatomopathologic study which confirms the clinical diagnosis and avoids performing excessive enucleation in case of benign tumors as adenoma.
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