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C Buys

Publications and source records attributed to C Buys.

7 recordsLinked to original sources
PubMed1989

Different haplotypes for cystic fibrosis-linked DNA polymorphisms in Polish and Dutch populations.

We analyzed DNA from 34 Polish and 63 Dutch cystic fibrosis (CF) patients and their families using the polymorphic markers XV2c and KM19, which are in linkage disequilibrium with the CF mutation. Strong linkage disequilibrium was found in the Dutch population sample, but the haplotypes of the Polish chromosomes showed a significantly less extreme disequilibrium. Our data and previous studies indicate that the highest degree of homogeneity of the CF defect and hence the best possible use of the XV2c/KM19/CF linkage disequilibrium for CF carrier detection/exclusion is in populations of northern European origin.

Cystic Fibrosis↗
PubMed1988

Prenatal diagnosis of cystic fibrosis using linked DNA probes.

This paper presents data collected in Europe on 107 prenatal diagnoses of cystic fibrosis (CF) using linked DNA markers. To date, 38 children have been born without CF, as predicted, demonstrating the present rapid move from research to clinical genetic service.

Adult↗