Biomedical subjects

C C Bremner

Publications and source records attributed to C C Bremner.

2 recordsLinked to original sources

PubMed1994

Gastric emptying and acid-output patterns following a suprapapillary duodenojejunostomy reconstruction with differing lengths of the afferent limb in the baboon.

The importance of afferent limb draining biliopancreatic secretions in Roux-en-Y type reconstructions has never been evaluated experimentally. The effects of the suprapapillary Roux-en-Y duodenojejunostomy operation using a constant duodenal and afferent limb length but a varying afferent limb length was assessed in three groups of five baboons. Gastric emptying, which was assessed preoperatively and postoperatively, was not changed in the baboons with a 12.5-cm-long afferent limb, was significantly delayed in the baboons with a 25-cm-long limb, and was significantly increased in the baboons with a 37.5-cm-long limb. Gastric acid control remained unchanged postoperatively.

Anastomosis, Roux-en-Y↗

PubMed1993

Motility differences between long-segment and short-segment Barrett's esophagus.

Barrett's esophagus has been described as a motility disorder of the esophagus, but the issue of whether or not the disorder precedes the columnar lining has been debated. Motility records of 70 patients with histologically proven Barrett's esophagus were analyzed. A comparison of the swallow responses was made between those patients who had a limited Barrett's segment (3 to 5 cm, n = 28) as opposed to those patients who had an extensive Barrett's segment (greater than 5 cm, n = 42). Patients with an extensive segment had a significantly lower amplitude (p < 0.01) of esophageal contraction and a significantly longer duration (p < 0.01) of contraction compared with patients with a limited segment. These differences were most marked in the distal esophageal segments. There was a progressive deterioration of esophageal motility with advanced disease.

Adult↗