PubMed Health⌕ Search

Biomedical subjects

C C Chi

Publications and source records attributed to C C Chi.

At least 19 recordsLinked to original sources
PubMed2005

Onychomycosis in Taiwan.

The pathogens of onychomycosis have implications in choosing therapy. We aimed to survey the pathogens of onychomycosis in Taiwan and further analyse the distribution of pathogens in various conditions. We also compared the distribution of pathogens in Taiwan with those in various countries. This study included 182 cases of onychomycosis who attended our clinic between January and December 2001. Histopathologic examination and fungus culture of the nail specimens were performed to confirm the diagnosis and identify the pathogens. The pathogens were dermatophytes in 101 patients (55.5%), Candida in 66 (36.3%), and non-dermatophyte moulds in 16 (8.2%). Candida was more frequently seen in patients older than 60 years (40.9%), females with fingernail onychomycosis (66.7%) or combined fingernail and toenail onychomycosis (58.3%), and presence of paronychia (57.9%). Dermatophytes are the predominant pathogens in temperate Western countries; meanwhile, Candida and non-dermatophyte moulds are prevailing in Mediterranean and tropical countries including Taiwan. Clinicians should appreciate that the pathogens of onychomycosis may vary in different patient groups and geographical locations, and choose optimal antifungal agents accordingly.

Adult↗
PubMed1991

Recurrent acute encephalopathy due to fatty acid metabolic defect--report of two cases.

An increasing number of reports indicate that patients with some inherited metabolic diseases may have symptoms resembling those of Reye's syndrome. We describe 2 patients who developed Reye-like syndrome at the age of 7 months respectively. Conscious disturbance, hepatomegaly, impaired liver function, hyperammonemia, and nonketotic hypoglycemia were noted during acute episode. Blood lactate level was normal in both cases. Liver and muscle biopsy of both patients showed macrovesicular fatty change. Increased density of matrix in hepatocyte mitochondria was noted in patient 1. Stacking of cristae was shown in patient 2. The first patient had another episode of hyperammonemia at 2 years of age. The second patient was admitted three more times due to recurrent vomiting and conscious change at the age of 7 months, 10 months and 13 months respectively. Fatty acid metabolic defect should be considered in children or infants with recurrent Reye-like syndrome.

Acute Disease↗
PubMed1990

[Study of rat control by using bait box].

This study examines the feasibility of using bait boxes for permanent rat control in Taiwan. During the test period between October 1988 and March 1989, 37 bait boxes made of PVC pipes were placed at various baiting sites in public markets, near restaurants and food stands in several communities known to be infested by rats. Each of the 37 boxes was baited with non-toxic rice powder to determine how well these boxes were accepted, the time needed for rats to use the boxes and eat the bait, and to do preliminary census on the relative densities of rat populations at these different places. The results showed that 27 of 29 (93.1%) bait boxes that had not been vandalized, disturbed or moved away and could be monitored continuously were used by rats. Of these 27 bait boxes, 13 (48.1%) were used the day after the boxes were set, and 25 (92.6%) were used within a week after the boxes were set. The amount of bait eaten per day for each bait box varied greatly, from less than 5 g to more than 300 g. After the bait in each bait box was taken regularly, half of the bait boxes with good bait acceptance were pulse-baited with 0.005% brodifacoum coated rice powder, and the other half of the bait boxes with good bait acceptance were baited with non toxic rice powder for comparison. The result of treatment indicated that rat control by using bait boxes is effective. However, the cooperation of the local people and the location of bait boxes have a great influence over the success of this control method.

Animals↗
PubMed1989

Efficacy of carbamazepine in assaultive patients with frontal lobe dysfunction.

1. A double-blind pilot study using a reversal design was conducted to examine the efficacy of carbamazepine in four cases of assaultiveness associated with frontal lobe dysfunction compared to five control cases. 2. Frontal lobe patients who received carbamazepine demonstrated a pattern of improvement on all cognitive, affective, and behavioral measures. This was followed by return to pretreatment level (measures of assaultiveness, depression, and general cerebral efficiency) or sustained improvement (measures of frontal lobe efficiency) when carbamazepine was discontinued. Control subjects showed only minimal differences across testing.

Adult↗
PubMed1978

Diphenylhydantoin teratogenicity in man.

A case is presented of fetal teratogenic damage from an unusually high maternal dosage of diphenylhydantoin, 600 mg daily, to a 40-kg woman throughout pregnancy. The anomalies included narrowed ends of the fingers and toes; aplasia of the nails on the other fingers and toes; aplasia of the distal phalanges of the fingers and toes; a broad, depressed nasal bridge; anteverted nostrils; prominent upper lip; coarse, profuse scalp hair; pilonidal sinus; and simian crease of the left hand. At the age of 7 months, ossification of the distal phalanges of both middle fingers appeared, the anterior fontanel was small, brain development was retarded, cranial asymmetry was marked, and the fingertips showed a pattern of low arch dermal ridges.

Abnormalities, Drug-Induced↗
PubMed1976

Neuroanatomic projections related to biting attack elicited from ventral midbrain in cats.

A single electrode was implanted in each of ten cats at a point in the ventral midbrain from which nonaffective biting attack on a rat could be elicited by electrical stimulation. A lesion was then made which was just large enough to eliminate the elicitation of attack at suprathreshold intensities from that electrode. After post-lesion survival times of 3-14 days the cats were sacrificed, and the degeneration resulting from the lesions was followed with the use of modified Nauta silver stains. Four additional cats were used as anatomic controls. Degenerating fibers were observed to descend bilaterally through the midbrain, pontine, and medullary tegmentum to the vicinity of the principal sensory and motor nuclei of the trigeminal nerve. There was, in addition, evidence of degenerating terminals within the nucleus of the facial nerve and the spinal nucleus of the trigeminal nerve. Of particular note was the observation that the degenerating fibers in the region of the nucleus of the spinal tract of the trigeminal nerve terminated in glomeruli in the rostral portion of the nucleus. Degenerating fibers ascending from the lesion were found to course along the medial forebrain bundle into the hypothalamus and the midline thalamus in a pattern very similar to that previously demonstrated after lesions of biting attack sites in the hypothalamus. The role that the neural pathways associated with ventral midbrain attack sites might play in the mediation of behavior patterns which are elicited during attack stimulation was discussed and it was concluded that the demonstrated neural pathway could provide a cogent explanation for some of the properties of centrally elicited attack behavior.

Affect↗
PubMed1972

Biting attack elicited by stimulation of the ventral midbrain tegmentum of cats.

An area in the ventral midbrain tegmentum has been discovered in which electrical stimulation elicits biting attack. The midbrain sites from which attack was elicited correspond well with the zone in the midbrain tegmentum where degeneration was previously observed after lesions were made in lateral hypothalamic attack sites.

Aggression↗
PubMed1971

Neural pathways associated with hypothalamically elicited attach behavior in cats.

Small electrolytic lesions were made in cats through electrodes, which, when stimulated, elicited either quiet biting attack or affective paw strike attack upon rats. The Nauta method for impregnating degenerating axoplasm was used to reveal that degeneration resulting from lesions at quiet attack sites followed largely along the course of the medial forebrain bundle, while the degeneration after lesions of affective attack sites was concentrated more heavily in the periventricular system.

Aggression↗