PREPARATION OF A NERVE-STIMULATING PHOSPHOPEPTIDE (SUBSTANCE B, NERVESIDE) IN BRAIN EXTRACTS AND AN ENZYME IN BRAIN WHICH INACTIVATES IT.
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Acid Phosphatase↗
Biomedical subjects
C C TOH
Publications and source records attributed to C C TOH.
Biologically active substances in brain extracts.
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Brain↗
A THERAPEUTIC TRIAL OF A NEW ANTICHOLINERGIC DRUG, OXYPHENCYCLIMINE HYDROCHLORIDE, ON PATIENTS WITH PEPTIC ULCERS.
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Cholinergic Antagonists↗
Aldosterone antagonist (spironolactone) as an adjunct in the management of ascites in cirrhosis of the liver.
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Antihypertensive Agents↗
Natural history of Streptococcus faecalis endocarditis.
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Endocarditis↗
Effects of temperature on the 5-hydroxytryptamine (serotonin) content of tissues.
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Serotonin↗
A case of malignant granuloma of the nose.
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Disease↗
Vasoactive substances in the nasal mucosa.
Besides histamine another smooth muscle stimulating substance has been found in the nasal mucosa of dog and sheep. It is an acid which is readily oxidized by neutral aqueous potassium permanganate and osmium tetroxide, and is thermostable at pH 10.8 but not at pH 2.8. The purification of this acid has been followed by using the atropinized tortoise intestine as a test object, which is insensitive to acetylcholine, 5-hydroxytryptamine and small amounts of histamine. Both the tortoise intestine and rat colon are contracted by this acidic substance. The amount of histamine found in sheep nasal mucosa ranged from 12 to 23 mug./g. tissue and in dog nasal mucosa from 6 to 13 mug./g. tissue.
Acetylcholine↗
The presence of a 5-hydroxytryptamine (serotonin) liberator in the gastro-intestinal tract.
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Gastrointestinal Tract↗
Release of 5-hydroxytryptamine (serotonin) and histamine from platelets by tissue extracts.
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Blood Platelets↗
The pharmacological actions of capsaicin and analogues.
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Acetates↗
Release of 5-hydroxytryptamine (serotonin) from the dog's gastrointestinal tract.
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Animals↗
Absorption of serotonin (5-hydroxytryptamine) and histamine by dog platelets.
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Animals↗
Fractionation of the smooth muscle stimulants present in extracts of gastro-intestinal tract. Identification of 5-hydroxytryptamine and its distinction from substance P.
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Central Nervous System Stimulants↗
The respiratory stimulant action of 5-hydroxytryptamine (serotonin) in the dog.
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Animals↗
Distribution of 5-hydroxytryptamine (serotonin, enteramine) in the wall of the digestive tract.
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Gastrointestinal Tract↗
The effect of 5-hydroxytryptamine (serotonin) on respiration in the dog.
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Animals↗
Smooth muscle stimulants from the gastrointestinal tract; identification of 5-hydroxytryptamine and its distinction from substance P.
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Gastrointestinal Tract↗