Biomedical subjects

C Cann

Publications and source records attributed to C Cann.

20 records · Page 2Linked to original sources

PubMedDate not supplied

[The state of bone tissue in monkeys in experiments in the Cosmos-1887 biosatellite].

Using invasive and noninvasive techniques, we studied bone changes in primates flown for 13 days on Cosmos-1887 and compared them with the data obtained from vivarium control animals and from the flown primates that were after flight exposed to a ground-based synchronous experiment in the biosatellite mockup. It was found that bone density in the diaphysis of the tibia decreased while its growth rate remained unchanged or diminished. Contact X-raying indicated a higher rate of endosteal resorption in the flown primates when compared with the controls. Histomorphometric measurements of iliac bioptates displayed signs of inhibited bone formation after flight. The above observations are discussed and compared with the results obtained in previous biosatellite flights and ground-based studies.

Animals↗

PubMedDate not supplied

[Study of the musculoskeletal system of the spine in humans after long-term space flights by the method of computerized tomography].

By computer tomography, mineral density of lumbar vertebrae and their segments as well as back muscle (++ilio-costal, extensor and ++inter-spinal) density and mass were measured in four Salyut-7 crewmembers before and after extended flights (of 5 and 7 months in duration). These findings are in good agreement with the results of prolonged bed rest studies in which trabecular bone of vertebral bodies was investigated: mineral density diminished only in some (approximately 10%) of the test subjects. At the same time mineral density loss was seen in the vertebral elements where muscles were attached. Also, muscle mass was reduced. It is emphasized that the level of changes was not correlated with flight time. Further investigations in this area are discussed.

Aerospace Medicine↗