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Biomedical subjects

C Cappelen

Publications and source records attributed to C Cappelen.

18 recordsLinked to original sources

Naloxone-induced reduction of schizophrenic symptoms.

A schizophrenic patient was repeatedly treated with intravenous naloxone 0.04 mg or saline in a double-blind design. The Comprehensive Psychopathological Rating Scale was used to quantify the symptoms before and after each injection. Naloxone significantly reduced the symptoms temporarily, whereas saline was without effect.

Adult

The adhesiveness of blood platelets before, during and after cardiopulmonary bypass.

The influence of cardiopulmonary bypass on the adhesiveness of blood platelets, using both bubble (Bentley and Rygg-Kyvsgaard) and membrane (Landé-Edwards) oxygenators, was investigated. With both types of oxygenators, there was a considerable fall in platelet adhesiveness during cardiopulmonary bypass, particularly with the Rygg-Kyvsgaard apparatus. The adhesiveness increased 30 minutes after bypass, but it was still not restored to the initial value.

Cardiopulmonary Bypass

Intra-aortic balloon pumping in the treatment of cardiogenic shock following open-heart surgery.

Intra-aortic balloon pumping (IABP) was used in the treatment of 29 patients in cardiogenic shock refractory to pressor drugs subsequent to open-heart surgery. Nineteen patients recovered from the shock primarily, but four died later in hospital. The remaining 15 were discharged alive. Peroperative electromagnetic flow measurements in one patient showed a 23% increase in aortic flow and a 26% increase in aortocoronary bypass flow when pumping was started.

Adult