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Biomedical subjects

C Carballo Fernández

Publications and source records attributed to C Carballo Fernández.

12 recordsLinked to original sources

[Uveal lymphoid infiltration with systemic extension].

CASE REPORT: We report the case of a patient who was surgically treated in his right eye because of an uncontrollable glaucoma and a retinal detachment without retinal break. Ultrasound and computed tomography showed diffuse choroidal thickening. During 6 years of follow-up, he developed a major ocular and orbitary invasion and bone marrow infiltration. He was treated by enucleation and chemotherapy with apparent total remission. DISCUSSION: Reactive lymphoid hyperplasia of the uvea consists of a lymphocytic proliferation that primarily involves the uveal tract. This process is regarded as a low malignant condition, but this case of late diagnosis showed a tendency to orbital and systemic extension.

Aged↗

[Pentachlorophenol poisoning. Report of 4 cases and review of the literature].

Pentachlorophenol (PCP) was, and still is, one of the most frequently used fungicides and pesticides. The use of PCP has been more restricted during the last few years. PCP's most important industrial application is as a wood preservative. The pentachlorophenol can be absorbed into the body by all the routes of occupational exposure. Some epidemiological observations suggest that exposure to PCP solutions may result in an increased risk for certain diseases in humans, e.g., immunodeficiency, blood disorders, malignancies, congenital anomalies. Chronic poisoning is difficult to detect since symptoms are often vague. Acute poisoning is due to interference with oxidative phosphorylation and can present itself as an unexpected case of sudden death. Four cases of PCP poisoning, including one fatalitie, occurred in two small wood preservative plants. All cases presented with increased serum creatinine phosphokinasa. The clinical finding are reported, and treatment modalities commented. At present there is no antidote for PCP. The basis for treatment is intensive supportive care to maintain vital bodily function. In one patient plasmapheresis was used and rapid recover was obtained. It is suggested that such therapy may be lifesaving in such intoxications.

Adult↗

[Whipple's disease and splenomegaly with negative intestinal biopsies].

A case is presented of a patient with a picture of acute gastroenteritis and splenomegaly. Microscopic study of the spleen and a lymph node showed the characteristic findings of Whipple's disease, although no digestive alteration was found, in spite of performing several duodenal and jejunal biopsies. The etiopathogenesis of this entity is commented on and discussed.

Adult↗

[Recurrent Budd-Chiari syndrome as a complication of nocturnal paroxysmal hemoglobinuria].

Budd-Chiari syndrome is a frequent complication of nocturnal paroxysmal hemoglobinuria, histologic and angiographic study being fundamental for diagnosis. We emphasize the importance of ultrasonography and abdominal CAT as noninvasive methods of early diagnosis, and the value of ultrasonography in the follow-up of these patients. Radical therapy of the disease from onset is a determinant of the final prognosis of these patients, as well as early treatment of thrombosis with thrombolytics and/or anticoagulants.

Aged↗