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Biomedical subjects

C Carrère

Publications and source records attributed to C Carrère.

9 recordsLinked to original sources
PubMed2005

[Ulcerating haemorrhagic colitis induced by celecoxib].

INTRODUCTION: Selectivity of cyclooxygenase-2 inhibitors (Cox2 inhibitors) decreased gastroduodenal toxicity of nonsteroidal anti-inflammatory drugs. Effects on colic mucosa are little known. OBSERVATION: A case history is described of a 38-year-old women, without digestive past, who presented with hemorrhagic ulcerated acute colitis beginning 2 days after starting celecoxib (200 mg/d) prescribed for sciatica. DISCUSSION: Intrinsic imputability of celecoxib is very probable in this case report by combination of chronological and semiological criteria. Extrinsic imputability is discussed, starting from the available bibliographical data which relate primarily to rofecoxib. CONCLUSION: This observation, which constitutes, as far as we know, the first case report of hemorrhagic ulcerated colitis related to celecoxib, confirms the colic toxicity of anti-Cox2 and identify a new cause of acute colitis. Report of colic side effects with Cox2 inhibitors is required because of their new marketing.

Acute Disease↗
PubMed2000

[Marchiafava-Bignani disease of good prognosis. Two cases].

BACKGROUND: Marchiafava-Bignami disease or corpus callosum necrosis, is an uncommon complication of chronic alcoholism. Prognosis is severe. CASE REPORTS: Two young adults with chronic alcoholism who developed Marchiafava-Bignami disease initially improved clinically. DISCUSSION: Diagnosis has been facilitated with MRI. An MRI exploration should be performed in chronic alcoholic patients presenting chronic encephalopathy with dementia, dysarthria, hypertonia, and ataxia, or acute encephalopathy with confusion, dumbness, seizures, and hypertonia. Necrosis of the corpus callosum gives the diagnosis of Marchiafava-Bignami disease.

Adult↗
PubMed1983

[Public health problems posed by the occurrence of Haemophilus meningitis in limited communities and especially its chemophophylaxis].

In Val-de-Marne District there is a permanent medical network to check up all cases of infectious meningitis. H. influenzae meningitis are increasing and represent 25% of all purulent meningitis (mainly infants of less than 6 years old) diagnosed in this area, second only to the meningococcus. English authors find Haemophilus influenzae to be as contagious as the meningococcus. Public Health physicians have to know these informations in order to prevent infection in communities; systematic throat culture with antibiograms, regular medical check-up, disinfection, exclusion from school and the choice of prophylactic anti-biotherapy are discussed. Many drugs have been proposed ampicillin, rifampicin, spiramycin, erythromycin, pristinamycin, tetracyclin. None of them managed to get a unanimous approval. The probably temporary solution is to follow the same guidelines than for the meningococcus infections and contaminations. They are described in details in the n degrees 8 Ministerial Memorandum dated January 28, 1980. About chimioprophylaxy, the physicians have to judge any single case as a whole. First ENT infections in those communities have to be totally treated.

Anti-Bacterial Agents↗