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Biomedical subjects

C Cassano

Publications and source records attributed to C Cassano.

At least 19 recordsLinked to original sources
PubMed2000

[Classification by occupation of AIDS cases in Brazil - 1995].

Based on occupational classification of AIDS cases reported in Brazil in 1995 and recorded in the Data Base for Reported Diseases (SINAN), AIDS incidence rates were estimated per 100 thousand inhabitants by occupation, according to the 1991 National Census. Nationwide rates for employed males and females were 25.0 and 9.1, respectively. Among males, and within the major occupational groups, the following sub-groups had the highest rates: personal hygiene services (268.1), social scientists (176.1), writers and journalists (114.3), medical and dental assistants (113.4), chemists, pharmacists, and physicists (111.9), teachers (87.3), artists (74.7), port services (65.6), maritime and fluvial transportation (57.5), and sales personnel (55.4). The results indicated the disease's magnitude in different occupational categories and highlighted certain occupations in which special preventive measures are justified, along with more in-depth studies focusing on other socioeconomic variables and the sociocultural behavior of their members.

Acquired Immunodeficiency Syndrome↗
PubMed1999

Assignment of human teratocarcinoma derived growth factor (TDGF) sequences to chromosomes 2q37, 3q22, 6p25 and 19q13.1.

The human teratocarcinoma derived growth factor 1 (TDGF1) gene maps on chromosome (Chr) 3p21.3. One pseudogene (TDGF3) maps on Chr Xq21-->q22. We now report the nucleotide sequence and chromosome location of three additional TDGF pseudogenes. The three new sequences (TDGF2, TDGF4 and TDGF5) are truncated at the 5' end and have accumulated several point mutations, deletions and insertions. TDGF2, TDGF4 and TDGF6 map on Chrs 2q37, 6p25 and 3q22, respectively. Finally, Southern blot analysis of DNA from normal individuals shows a highly variable restriction pattern of the TDGF sequences.

Alu Elements↗
PubMed1996

Assignment of the vascular endothelial growth factor gene to human chromosome 6p21.3.

BACKGROUND: Vascular endothelial growth factor (VEGF) is an endothelial cell-specific growth factor and a regulator of physiological and pathological angiogenesis. Four different proteins are produced by alternative splicing of a unique transcript generated from a single-copy gene. Knowledge of the chromosomal location of the VEGF gene would help in determining a linkage to any known human congenital syndrome and/or to known chromosomal rearrangements in tumors. METHODS AND RESULTS: A human chromosome mapping panel was used to assign the VEGF gene to human chromosomes by polymerase chain reaction using VEGF-specific oligonucleotide primers. Amplified DNA fragments were fractionated on a 1% agarose gel. A single band of the expected size was obtained only from the DNA of those hybrid cell lines that contained the human chromosome 6. Three YAC clones containing the VEGF gene were obtained by screening the ICI Diagnostics library. In situ hybridization was then used to locate the VEGF gene in the 6p21.3 region. CONCLUSIONS: The location of the VEGF gene in the 6p21.3 region is a potential starting point for a linkage study. In addition, the isolation of YAC clones containing the VEGF gene will contribute to the construction of the physical map of this chromosomal region.

Base Sequence↗